Esophageal atresia
MONDO:0001044A congenital abnormality of the esophagus in which the upper esophagus ends as a blind pouch and does not connect with the lower esophagus; it is often accompanied by a tracheoesophageal fistula. Signs and symptoms in a newborn with this abnormality include excessive salivation, choking, coughing, and the development of cyanosis and respiratory distress when fed.
Also known as: congenital atresia of esophagus, congenital atresia of oesophagus, congenital esophageal atresia, congenital imperforate oesophagus, esophageal atresia, esophageal atresia (disease), imperforate oesophagus
18 clinical trials for this condition and its sub-types, 12 tagged with Esophageal atresia itself.
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Sub-types of Esophageal atresia
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Arroyo Garcia Cimadevilla syndrome 0 trials
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Could a simple timing change improve treatment for kids with narrowed esophagus?
Symptom relief Recruiting nowThis study looks at children born with esophageal atresia who develop narrowing (strictures) after surgery. Doctors use a balloon to stretch the narrowed area, but it's unclear how long the balloon should stay inflated. The trial will compare 30 seconds versus 180 seconds of infl…
Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Teens born with a rare esophagus condition studied for lifelong health clues
Knowledge-focused Recruiting nowThis study follows 300 teenagers born with esophageal atresia, a condition where the esophagus is not fully formed at birth. Researchers will track common long-term problems like acid reflux, breathing issues, and growth, and collect blood and tissue samples to look for biologica…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Timing of birth defect diagnosis may impact parent trauma
Knowledge-focused Recruiting nowThis study measures and compares post-traumatic stress in mothers (and some fathers) of children born with esophageal atresia, a condition where the esophagus doesn't connect properly. Researchers want to see if learning about the condition before birth (antenatal) versus after b…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New study aims to unlock dangerous blood sugar drops in infants
Knowledge-focused Recruiting nowThis study looks at why some babies born with esophageal atresia develop dumping syndrome, a condition causing dangerous blood sugar drops after feeding. Researchers will monitor 15 infants with continuous glucose and heart monitors and a stomach-emptying scan at 3 months old. Th…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Baby blood test may predict surgical recovery
Knowledge-focused Recruiting nowThis study measures two natural amino acids, arginine and ADMA, in newborns who had abdominal surgery within their first 5 days of life. Researchers want to see if the balance of these substances can help predict how quickly a baby recovers and whether complications arise. No ext…
Sponsor: Liverpool Women's NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC