Epidermolysis bullosa simplex

MONDO:0017610

Epidermolysis bullosa simplex (EBS) is a group of hereditary epidermolysis bullosa (HEB) disorders characterized by skin fragility resulting in intraepidermal blisters and erosions that occur either spontaneously or after physical trauma.

Also known as: EBS, EEB, epidermolysis bullosa simplex, epidermolysis bullosa intraepidermic

6 clinical trials for this condition and its sub-types, 5 tagged with Epidermolysis bullosa simplex itself.

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Where it sits in the disease tree

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↑ Inherited epidermolysis bullosa (37)

Sub-types of Epidermolysis bullosa simplex

Epidermolysis bullosa simplex 1B, generalized intermediate 1 trial
Epidermolysis bullosa simplex 1A, generalized severe 0 trials
Epidermolysis bullosa simplex 1C, localized 0 trials
Epidermolysis bullosa simplex 1D, generalized, intermediate or severe, autosomal recessive 0 trials
Epidermolysis bullosa simplex 2A, generalized severe 0 trials
Epidermolysis bullosa simplex 2B, generalized intermediate 0 trials
Epidermolysis bullosa simplex 2C, localized 0 trials
Epidermolysis bullosa simplex 2E, with migratory circinate erythema 0 trials
Epidermolysis bullosa simplex 2F, with mottled pigmentation 0 trials
Epidermolysis bullosa simplex 2d, generalized, intermediate or severe, autosomal recessive 0 trials
Epidermolysis bullosa simplex 3, localized or generalized intermediate, with BP230 deficiency 0 trials
Epidermolysis bullosa simplex 4, localized or generalized intermediate, autosomal recessive 0 trials
Epidermolysis bullosa simplex 5A, Ogna type 0 trials
Epidermolysis bullosa simplex 5B, with muscular dystrophy 0 trials
Epidermolysis bullosa simplex 5C, with pyloric atresia 0 trials
Epidermolysis bullosa simplex 6, generalized, with scarring and hair loss 0 trials
Epidermolysis bullosa simplex 7, with nephropathy and deafness 0 trials
Epidermolysis bullosa simplex with anodontia/hypodontia 0 trials
Epidermolysis bullosa simplex with nail dystrophy 0 trials
Suprabasal epidermolysis bullosa simplex 0 trials
3 sub-types
- Epidermolysis bullosa simplex due to plakophilin deficiency 0 trials
- Epidermolysis bullosa simplex superficialis 0 trials
- Lethal acantholytic epidermolysis bullosa 0 trials

Including sub-types (6) Tagged with Epidermolysis bullosa simplex (5)

Trials to join now! 2 Not yet recruiting 2 Not yet finished but already full! 1 Completed 1

New ointment could ease blistering in rare skin disease

Disease control Ongoing

This study tests an ointment called diacerein 1% on people with a rare genetic skin condition (EBS) that causes fragile skin and painful blisters. About 80 participants will apply the ointment daily to see if it clears blisters and reduces pain. The trial is double-blind, meaning…

Phase 2/3 • Sponsor: TWi Biotechnology, Inc. • Aim: Disease control

Last updated Jul 11, 2026 00:00 UTC

Epidermolysis bullosa simplex

Where it sits in the disease tree

New ointment could ease blistering in rare skin disease