Epidermolysis bullosa
MONDO:0006541Epidermolysis bullosa (EB) is a group of genetic skin diseases that cause the skin to blister very easily. Blisters form in response to minor injuries or friction, such as rubbing or scratching. There are four main types of epidermolysis bullosa: dystrophic epidermolysis bullosa Epidermolysis bullosa simplex Junctional epidermolysis bullosa Kindler Syndrome Identifying the exact type can be hard because there are many subtypes of EB. Within each type or subtype, a person may be mildly or severely affected. The disease can range from being a minor inconvenience to completely disabling, and fatal in some cases. Most types of EB are inherited. The inheritance pattern may be autosomal dominant or autosomal recessive. Management involves protecting the skin, reducing friction against the skin, and keeping the skin cool.
Also known as: epidermolysis bullosa, EB
44 clinical trials for this condition and its sub-types, 23 tagged with Epidermolysis bullosa itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Epidermolysis bullosa
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Inherited epidermolysis bullosa 5 trials · 37 incl. sub-types
4 sub-types
- Epidermolysis bullosa dystrophica 23 trials · 30 incl. sub-types Sub-types →
- Junctional epidermolysis bullosa 6 trials · 8 incl. sub-types Sub-types →
- Epidermolysis bullosa simplex 5 trials Sub-types →
- Kindler syndrome 0 trials Sub-types →
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Acquired epidermolysis bullosa 3 trials
Most studied deeper sub-types
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Could your own belly fat fix ED after prostate cancer surgery?
Disease control CompletedThis study tested whether a single injection of a patient's own fat-derived stem cells into the penis could improve erectile dysfunction after prostate removal. 70 men who had poor erections for over a year after surgery were enrolled. Half received the stem cell injection, half …
Phase 2 • Sponsor: Odense University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New Wound-Cleaning pad could speed healing
Symptom relief CompletedThis study tests a new two-sided pad (Debrisoft Duo) for cleaning wounds by removing dead tissue. About 104 adults with various wound types (like diabetic ulcers or burns) will be randomly assigned to the new pad or the current one-sided pad. The main goal is to see if the new pa…
Sponsor: Lohmann & Rauscher • Aim: Symptom relief
Last updated Sep 05, 2026 00:00 UTC
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New hope for painful bandage changes in rare skin disease
Symptom relief CompletedThis study tested whether a numbing cream (ropivacaine) can reduce severe pain during bath and dressing changes in children and young adults with epidermolysis bullosa, a rare genetic skin condition. Ten participants applied the cream before dressing changes and reported their pa…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Rare skin disease study uncovers reasons kids avoid painkillers
Knowledge-focused CompletedThis study looked at why children with hereditary epidermolysis bullosa (a rare condition causing fragile skin and painful blisters) often do not take prescribed opioid painkillers before baths and bandage changes. Researchers interviewed 10 children and their parents to understa…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC