Could your own belly fat fix ED after prostate cancer surgery?
NCT ID NCT07355530
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a single injection of a patient's own fat-derived stem cells into the penis could improve erectile dysfunction after prostate removal. 70 men who had poor erections for over a year after surgery were enrolled. Half received the stem cell injection, half got a placebo. All had liposuction to harvest the cells. Researchers measured changes in erectile function using questionnaires over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Adipose-derived regenerative cells (stem cells from the patient's own fat)
- What this could lead to
- If it works, this could offer a new, one-time treatment for erectile dysfunction after prostate surgery, reducing the need for daily medication.
- What could go wrong
- This is a small, early-phase trial with only 70 participants. The treatment may not work better than placebo, and the effects may not last. All patients had liposuction, which carries its own risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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70 people
The number who actually took part.
- Started
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Jan 2018
- Finished
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Mar 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Nervesparing robot assisted RP * Erectile dysfunction for more than a year after RP * Normal erectile function before RP (IIEF-5 \> 22) and postoperative IIEF-5 score 5-20 or EHS 1 * Involved in a monogamous, heterosexual relationship (since questionnaires are only valid for heterosexual relationsships), where both parts are interested in sexual activities * Insufficient effect of standard medical treatment for ED * Subcutaneous adipose deposits on the abdomen \> 120 mL * Performance status 0 * Ability to give informed consent * Proficiency in the Danish language to understand the questionnaires IIEF-5 and EHS Exclusion criteria: * Problems with general anesthesia * Incontinence after RP * Anti-thrombotic treatment that cannot be discontinued or substituted with heparin * No interest in sexual interaction with a partner * Previous pelvic surgery or radiation * Systemic autoimmune disease * Alcohol or drug abuse
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Odense Universityhospital
Odense, 5000, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.