Endolymphatic hydrops
MONDO:0006744An accumulation of endolymph in the inner ear (labyrinth) leading to buildup of pressure and distortion of intralabyrinthine structures, such as cochlea and semicircular canals. It is characterized by sensorineural hearing loss; tinnitus; and sometimes vertigo.
31 clinical trials for this condition and its sub-types, 2 tagged with Endolymphatic hydrops itself.
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Sub-types of Endolymphatic hydrops
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Meniere disease 16 trials
3 sub-types
- Active cochlear Meniere disease 0 trials
- Active cochleovestibular Meniere disease 0 trials
- Active vestibular Meniere disease 0 trials
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Hope for Meniere's sufferers: new drug enters final testing phase
Disease control OngoingThis study tests a drug called SPI-1005 in 200 adults with Meniere's disease, a condition that causes hearing loss, ringing in the ears, and dizziness. Participants will take the drug twice a day for 6 or 12 months to see if it is safe and tolerable. The goal is to find a treatme…
Phase 3 • Sponsor: Sound Pharmaceuticals, Incorporated • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Hearing loss injection study pulled before it began
Disease control CancelledThis pilot study aimed to test whether a mixture of dexamethasone, hyaluronic acid, and a green dye could be safely injected into the ear to treat certain types of hearing loss that don't improve with standard treatments. The plan was to enroll 26 adults with sudden hearing loss,…
Phase 1/2 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Can a cochlear implant bring back hearing after tumor removal?
Disease control OngoingThis study tests whether a cochlear implant can safely and effectively restore hearing in people who become deaf in one ear after surgery to remove a benign tumor (vestibular schwannoma) or to treat Meniere's disease. Fifteen participants will receive the implant during their sur…
Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Could a tiny jolt to the head diagnose balance problems?
Diagnosis By invitation onlyThis early study will test whether weak electrical currents applied to the head can help diagnose balance disorders like vestibular schwannoma and vestibular neuritis. Researchers will measure how 30 people with these conditions sway or move in response to the stimulation. The go…
Sponsor: Aalto University • Aim: Diagnosis
Last updated Jul 03, 2026 00:00 UTC
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Can a daily pill quiet the spinning of vertigo?
Symptom relief CancelledResearchers are testing an experimental oral tablet called APSLXR in people with Meniere's disease or vertigo of vestibular origin. The main goal is to check whether the drug is safe when taken once a day for 60 days. A small group will also have blood tests to see how the body p…
Phase 1 • Sponsor: Apsen Farmaceutica S.A. • Aim: Symptom relief
Last updated Sep 10, 2026 00:00 UTC
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6,000 patients, one big question: what really causes dizziness?
Knowledge-focused OngoingThis observational study will follow 6,000 adults with dizziness or vertigo who are receiving routine care at hospitals across China. Researchers aim to map the range of underlying causes, track how symptoms and diagnoses change over a year, and see how well standard treatments w…
Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Smart sensors could predict falls in older adults with dizziness
Knowledge-focused By invitation onlyThis study evaluates a sensor-based version of the Timed Up and Go test (QTUG) for measuring balance and predicting fall risk in older adults with dizziness (vestibulopathy). Researchers will compare QTUG results with other balance tests, track whether a six-month vestibular reha…
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC