Endogenous Cushing syndrome
MONDO:0957431Any Cushing syndrome caused by body's prolonged overproduction of cortisol that can be dependent on or independent of adrenocorticotropic hormone (ACTH).
Also known as: endogenous CS
40 clinical trials for this condition and its sub-types, 3 tagged with Endogenous Cushing syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Endogenous Cushing syndrome
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ACTH-dependent Cushing syndrome 23 trials · 26 incl. sub-types
2 sub-types
- Cushing disease due to pituitary adenoma 23 trials
- Ectopic Cushing syndrome 1 trial
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ACTH-independent Cushing syndrome 9 trials · 11 incl. sub-types
Most studied deeper sub-types
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New drug shows promise for Long-Term control of cushing syndrome
Disease control OngoingThis study looks at the long-term safety of relacorilant, a drug for people with Cushing syndrome. It includes 125 adults who previously completed a relacorilant study and may benefit from continued treatment. Researchers will track side effects over time to see if the drug is sa…
Phase 2 • Sponsor: Corcept Therapeutics • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Cushing's drug osilodrostat under Long-Term safety review
Disease control OngoingThis study follows 206 patients with Cushing's syndrome who are taking osilodrostat (Isturisa) to see how safe and effective it is over time. Researchers will track side effects and how well the drug controls cortisol levels. No new treatment is given—just real-world monitoring.…
Sponsor: RECORDATI GROUP • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC