Cushing syndrome due to macronodular adrenal hyperplasia
MONDO:0009049A rare adrenal Cushing syndrome characterized by bilateral benign adrenal macronodules (>1 cm) that potentially produce autonomously variable levels of cortisol excess. Although in most cases are ACTH-independent, non-suppressed ACTH levels have been described.
Also known as: ACTH-independent Cushing syndrome, ACTH-independent macronodular adrenal hyperplasia, primary bilateral macronodular adrenal hyperplasia, ACTH-independent macronodular adrenocortical hyperplasia, AIMAH, MMAD, adrenocorticotropic hormone-independent macronodular adrenal hyperplasia, corticotropin-independent macronodular adrenal hyperplasia
6 clinical trials for this condition and its sub-types, 3 tagged with Cushing syndrome due to macronodular adrenal hyperplasia itself.
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Browse by category →Sub-types of Cushing syndrome due to macronodular adrenal hyperplasia
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New imaging tracer could shed light on adrenal cholesterol
Knowledge-focused Recruiting nowThis study tests a special radioactive tracer called [18F]FNP-59 to see if it can safely and clearly show cholesterol activity in the adrenal gland using PET scans. About 24 people will take part, including healthy volunteers and those with known adrenal problems. The goal is to …
Early phase 1 • Sponsor: Benjamin Viglianti • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Cushing's patients wanted for Long-Term health tracking study
Knowledge-focused Recruiting nowThis study is not testing a new treatment. Instead, it follows 300 people aged 14 and older with Cushing's syndrome to collect data on their health before and after standard treatments like surgery, medication, or radiation. The goal is to build a registry that helps doctors unde…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC