Enamel caries

This trial tests two resin infiltration systems, ICON and I-Mate, to see which better masks white spot lesions on front teeth and matches the natural tooth color. Researchers will enroll 50 people aged 16 to 35 who have non-cavitated white spots, often from previous braces. Parti…

This study tests if a new bioactive varnish can fix white spot lesions on teeth better than standard fluoride varnish. About 60 people aged 16-35 with at least four white spots will get one of the two varnishes. Researchers will check how well the spots heal and if tooth color im…

This study tests whether silver diamine fluoride or silver fluoride, sometimes with a special LED light, can stop early cavities in the back teeth of young adults. About 366 high-risk dental students will receive one of these treatments. The goal is to see which approach works be…

This study compares two types of dental glue used to attach braces to teeth. One is a traditional three-step system, the other a simpler two-step system. The goal is to see which causes less damage (white spots) to tooth enamel. Thirty-four teenagers will have each type of glue u…

Researchers are testing a device called BlueCheck to see if it can reliably find early enamel lesions and track how they change over 12 weeks. Participants aged 13 and older with active enamel lesions but no cavities needing immediate fillings receive high-fluoride toothpaste and…

This study compares artificial intelligence analysis of dental photographs to standard clinical exams for detecting white spot lesions—early signs of tooth decay. Researchers will train AI models (YOLO and Mask-RCNN) on 329 labeled images from adult patients at Cairo University D…

This trial tests whether a fluoride-releasing adhesive used to attach braces can prevent white spot lesions—early signs of decay—on teeth. About 40 adolescents getting braces will have standard adhesive on one side of their upper jaw and the fluoride sealant on the other. After 3…

This study tests how well three different toothpastes repair early tooth damage (enamel lesions) in 30 healthy adults aged 18-70. Participants wear a removable mouth device with human enamel pieces for 14 days per toothpaste, with breaks in between. Researchers measure mineral ga…