Early-onset autosomal dominant Alzheimer disease

MONDO:0015140

A progressive dementia with reduction of cognitive functions. It presents the same phenotype as sporadic Alzheimer disease (AD) but has an early age of onset, usually before 60 years old.

Also known as: EOFAD, early-onset familial autosomal dominant Alzheimer disease, early-onset, autosomal dominant Alzheimer disease

40 clinical trials for this condition and its sub-types, 31 tagged with Early-onset autosomal dominant Alzheimer disease itself.

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Where it sits in the disease tree

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↑ Autosomal dominant disease (699) ↑ Familial Alzheimer disease (55)

Sub-types of Early-onset autosomal dominant Alzheimer disease

Alzheimer disease 3 5 trials
Alzheimer disease type 1 4 trials
Alzheimer disease 4 3 trials
Alzheimer disease 10 1 trial
Alzheimer disease 11 1 trial
Alzheimer disease 12 1 trial
Alzheimer disease 13 1 trial
Alzheimer disease 14 1 trial
Alzheimer disease 5 1 trial
Alzheimer disease 6 1 trial
Alzheimer disease 7 1 trial
Alzheimer disease 8 1 trial
Alzheimer disease without neurofibrillary tangles 1 trial
Alzheimer disease, familial early-onset, with coexisting amyloid and prion pathology 0 trials

Including sub-types (40) Tagged with Early-onset autosomal dominant Alzheimer disease (31)

Trials to join now! 14 Not yet recruiting 2 Not yet finished but already full! 10 Completed 4 Terminated 1

Could a High-Fat diet boost brain health in early Alzheimer's?

Symptom relief Stopped early

This study looks at whether a ketogenic diet (high-fat, low-carb) is practical and safe for people with early-stage Alzheimer's disease over one year. The diet may provide an alternative energy source for the brain and reduce inflammation. Researchers will track diet adherence, b…

Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief

Last updated Sep 12, 2026 00:00 UTC

Early-onset autosomal dominant Alzheimer disease

Where it sits in the disease tree

Could a High-Fat diet boost brain health in early Alzheimer's?