Duodenum cancer

This trial tests whether giving three treatments together—two medicines and a surgical patch—can lower the risk of major complications after Whipple surgery for pancreatic cancer and other tumors. The study includes 400 high-risk patients with a small pancreatic duct. If successf…

This phase 3 trial tests whether adding a surgical glue called N-butyl-2-cyanoacrylate to standard pancreatic surgery can prevent postoperative pancreatic fistula—a common and serious leak of digestive fluids. About 194 patients with soft pancreas tissue undergoing tumor removal …

This study tests whether a rectus sheath block using long-acting liposomal bupivacaine can control pain as well as the standard thoracic epidural after pancreatic surgery. About 78 adults undergoing open pancreaticoduodenectomy will be randomly assigned to one of the two methods.…

This study looks back at 1,000 patients who had endoscopic resection—a minimally invasive procedure to remove abnormal growths—in the duodenum or ampulla over a 15-year period. The goal is to see how often the lesions come back, how often cancer develops, and what complications o…

This study is building a huge registry of information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. Researchers will use this resource to study what causes cancer and how to better prevent, detect, and treat it. The re…

This study looks back at medical records of 2000 adults who had endoscopic removal of cancerous or precancerous growths in the esophagus, stomach, duodenum, colon, or rectum. The goal is to compare different removal methods to see which works best and has the fewest complications…

This study aims to create a more accurate way to predict duodenal cancer risk in people with familial adenomatous polyposis (FAP), a genetic condition that greatly increases the chance of developing this cancer. Researchers will analyze endoscopy images from 300 participants to d…