Drug-induced liver injury
MONDO:0005359A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to acute liver failure, caused by drugs, drug metabolites, and chemicals from the environment.
Also known as: drug induced hepatotoxicity, drug-induced disorder of liver
24 clinical trials for this condition and its sub-types, 22 tagged with Drug-induced liver injury itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Drug-induced liver injury
-
Drug-induced hepatitis 3 trials
-
Blood cancer patients may get liver protection from common drug
Disease control Not yet recruitingThis real-world study looks at whether polyene phosphatidylcholine injection can prevent or treat drug-induced liver injury in adults with blood cancers like leukemia and lymphoma. Researchers will review medical records of 1,000 patients to see how well the drug works and if it …
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
-
SAMe supplement may shield liver from chemo harm
Prevention Not yet recruitingThis study tests whether taking S-adenosylmethionine (SAMe), a natural supplement, can prevent liver injury caused by the chemotherapy drug oxaliplatin. About 30 adults with colorectal cancer that has spread to the liver will take SAMe pills daily for 3-6 months alongside their c…
Phase 2 • Sponsor: Cedars-Sinai Medical Center • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC
-
Which medicines and herbal products are damaging livers? egyptian hospital launches Two-Year hunt
Knowledge-focused Not yet recruitingResearchers at Al-Rajhi Liver Hospital in Assiut, Egypt, are studying drug-induced liver injury, a form of liver damage caused by prescription medicines, over-the-counter drugs, herbal products, or dietary supplements. The study has two parts: a review of past medical records fro…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Sep 21, 2026 18:00 UTC
-
TB drug liver risk under the microscope
Knowledge-focused Not yet recruitingThis study will track 220 adults being treated for tuberculosis (TB) or latent TB with the drug isoniazid. Researchers want to see how often the drug causes liver injury and what factors make it more likely. They will also look at how doctors manage this side effect in real-world…
Sponsor: ASST Fatebenefratelli Sacco • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC