Distal renal tubular acidosis

MONDO:0015827

A kidney disorder of impaired net acid secretion by the distal tubule characterized by hyperchloremic metabolic acidosis. Primary distal renal tubular acidosis is often associated with hypokalemia whereas acquired form may be associated with hypokalemia, hyperkalemia or normokalemia.

Also known as: Primary Distal Renal Tubular Acidosis, classic RTA, dRTA, distal renal tubular acidosis (disease), familial distal primary acidosis, renal tubular acidosis type 1, renal tubular acidosis, distal

3 clinical trials for this condition and its sub-types, 3 tagged with Distal renal tubular acidosis itself.

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Where it sits in the disease tree

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Sub-types of Distal renal tubular acidosis

Acquired distal renal tubular acidosis 0 trials
Inherited distal renal tubular acidosis 0 trials
2 sub-types
- Autosomal dominant distal renal tubular acidosis 0 trials
- Autosomal recessive distal renal tubular acidosis 0 trials Sub-types →

Most studied deeper sub-types

Renal tubular acidosis, distal, 2, with progressive sensorineural hearing loss (0) Renal tubular acidosis, distal, 3, with or without sensorineural hearing loss (0) Renal tubular acidosis, distal, 4, with hemolytic anemia (0)

Including sub-types (3) Tagged with Distal renal tubular acidosis (3)

Not yet finished but already full! 1 Completed 1 Terminated 1

Kidney acidosis drug study pulled before it began

Disease control Cancelled

This study was designed to check the long-term safety and effectiveness of a drug called ADV7103 in people with primary distal renal tubular acidosis, a rare kidney problem that leads to too much acid in the blood. It planned to include people who had been in an earlier study, as…

Phase 3 • Sponsor: Advicenne Pharma • Aim: Disease control

Last updated Jun 27, 2026 09:03 UTC

Distal renal tubular acidosis

Where it sits in the disease tree

Most studied deeper sub-types

Kidney acidosis drug study pulled before it began