Distal myopathy
MONDO:0018949Distal myopathy refers to a group of muscle diseases which share the clinical pattern of predominant weakness and atrophy beginning in the feet and/or hands.
Also known as: distal muscular dystrophy, distal myopathy, Miyoshi muscular dystrophy
8 clinical trials for this condition and its sub-types, 1 tagged with Distal myopathy itself.
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Sub-types of Distal myopathy
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Miyoshi myopathy 1 trial · 2 incl. sub-types
3 sub-types
- Miyoshi muscular dystrophy 3 1 trial
- Miyoshi muscular dystrophy 1 0 trials
- Miyoshi muscular dystrophy 2 0 trials
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Myopathy, distal, 5 1 trial
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MYH7-related skeletal myopathy 0 trials
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Autosomal dominant distal myopathy 0 trials
15 sub-types
- Finnish upper limb-onset distal myopathy 0 trials
- KLHL9-related early-onset distal myopathy 0 trials
- TARDBP-related predominantly upper-limb distal myopathy 0 trials
- Adult-onset distal myopathy due to VCP mutation 0 trials
- Asymetric thumb-handgrip weakness-distal myopathy 0 trials
- Calf-predominant weakness-gastrocnemius medialis atrophy-distal myopathy 0 trials
- Distal myopathy with posterior leg and anterior hand involvement 0 trials
- Distal myopathy with vocal cord weakness 0 trials
- Distal myopathy, Tateyama type 0 trials
- Distal myopathy, Welander type 0 trials
- Myofibrillar myopathy 2 0 trials
- Myofibrillar myopathy 3 0 trials
- Myofibrillar myopathy 4 0 trials
- Myopathy, myofibrillar, 9, with early respiratory failure 0 trials
- Tibial muscular dystrophy 0 trials
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Myopathy, distal, infantile-onset 0 trials
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Oculopharyngodistal myopathy 0 trials
5 sub-types
- Oculopharyngodistal myopathy 1 0 trials
- Oculopharyngodistal myopathy 2 0 trials
- Oculopharyngodistal myopathy 3 0 trials
- Oculopharyngodistal myopathy 4 0 trials
- Oculopharyngodistal myopathy 5 0 trials
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Experimental drug hopes to slow rare muscle disease in two patients
Disease control By invitation onlyThis early-stage trial tests a daily injection of ASA-001 in two adults with a rare genetic muscle disease (ADSS1 deficient myopathy). The main goals are to see if the drug is safe and if it can slow the disease. Participants will take the drug for 8 months and have clinic visits…
Phase 1 • Sponsor: Cure ADSSL1 • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Researchers hunt for muscle clues in rare dystrophy
Knowledge-focused OngoingThis pilot study looks at biomarkers in the blood of people with fragile sarcolemmal muscular dystrophy, a condition that makes muscle membranes weak. Researchers will collect blood samples at rest and after exercise during four 5-day hospital stays. The goal is to better underst…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Can MRI scans reveal the hidden pattern of muscle damage in a rare muscular dystrophy?
Knowledge-focused OngoingThis study aims to describe the pattern of muscle involvement in people with limb girdle muscular dystrophy caused by mutations in the anoctamin 5 gene. Researchers will collect and analyze MRI scans from 200 participants to see which muscles are affected and how much fat replace…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC