Dilated cardiomyopathy
MONDO:0005021Cardiomyopathy which is characterized by dilation and contractile dysfunction of the left and right ventricles. It may be idiopathic, or it may result from a myocardial infarction, myocardial infection, or alcohol abuse. It is a cause of congestive heart failure.
Also known as: dilated cardiomyopathy, familial dilated cardiomyopathy, idiopathic dilation cardiomyopathy, primary dilated cardiomyopathy
137 clinical trials for this condition and its sub-types, 76 tagged with Dilated cardiomyopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Dilated cardiomyopathy
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Familial dilated cardiomyopathy 7 trials · 61 incl. sub-types
29 sub-types
- Leber hereditary optic neuropathy 18 trials Sub-types →
- Familial isolated dilated cardiomyopathy 0 trials · 11 incl. sub-types Sub-types →
- Barth syndrome 5 trials
- Kearns-Sayre syndrome 5 trials
- Autosomal recessive limb-girdle muscular dystrophy type 2E 5 trials
- Emery-Dreifuss muscular dystrophy 2 trials · 4 incl. sub-types Sub-types →
- Autosomal recessive limb-girdle muscular dystrophy type 2C 4 trials
- Symptomatic form of muscular dystrophy of Duchenne and Becker in female carriers 4 trials
- Autosomal recessive limb-girdle muscular dystrophy type 2D 3 trials
- Histiocytoid cardiomyopathy 3 trials Sub-types →
- Autosomal recessive limb-girdle muscular dystrophy type 2F 2 trials
- PGM1-congenital disorder of glycosylation 1 trial
- Autosomal recessive limb-girdle muscular dystrophy type 2M 1 trial
- Autosomal recessive limb-girdle muscular dystrophy type 2W 1 trial
- Early-onset myopathy with fatal cardiomyopathy 1 trial
- DK1-congenital disorder of glycosylation 0 trials
- Cardiomyopathy, dilated, 100 0 trials
- Cardiomyopathy, dilated, 1LL 0 trials
- Cardiomyopathy, dilated, 1MM 0 trials
- Cardiomyopathy, dilated, 1QQ 0 trials
- Cardiomyopathy, dilated, 2I 0 trials
- Cardiomyopathy, dilated, 2K 0 trials
- Cardiomyopathy, dilated, 2M 0 trials
- Cardiomyopathy, dilated, 2j 0 trials
- Cardiomyopathy, dilated, 2l 0 trials
- Cardiomyopathy, dilated, 3C 0 trials
- Dilated cardiomyopathy 1J 0 trials
- Hypertrophic cardiomyopathy 25 0 trials
- Myofibrillar myopathy 1 0 trials
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Non-familial dilated cardiomyopathy 3 trials · 11 incl. sub-types
2 sub-types
- Cirrhotic cardiomyopathy 4 trials
- Peripartum cardiomyopathy 4 trials
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Viral dilated cardiomyopathy 0 trials
Most studied deeper sub-types
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New heart drug AZD0233 begins first safety tests in healthy volunteers
Disease control Stopped earlyThis early-stage trial tested the safety of a new drug called AZD0233 in 84 healthy adults aged 18 to 50. The drug is being developed for dilated cardiomyopathy, a condition where the heart becomes enlarged and weak. Participants received either the drug or a placebo, and researc…
Phase 1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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Experimental gene therapy for rare muscle disease shows early promise but study halted
Disease control Stopped earlyThis study tested a gene therapy called SRP-9003 for people with limb-girdle muscular dystrophy type 2E (LGMD2E), a rare genetic disease that causes muscle weakness. The treatment aimed to deliver a working gene to muscle cells to help them produce a missing protein. Only 6 peopl…
Phase 1/2 • Sponsor: Sarepta Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Experimental gene therapy tested for rare muscular dystrophy
Disease control Stopped earlyThis early-stage trial tested a gene therapy called SRP-9004 in just 4 people with limb girdle muscular dystrophy type 2D/R3, a rare muscle-weakening disease. The main goal was to check safety, not effectiveness. The study was terminated early, so results are limited.
Phase 1 • Sponsor: Sarepta Therapeutics, Inc. • Aim: Disease control
Last updated Jun 26, 2026 13:47 UTC