Diffuse glioma, H3 G34 mutant
MONDO:0957197A histone mutated tumor that has material basis in mutations in codon 34 of the H3 histone family 3A protein.
1459 clinical trials for this condition and its sub-types, 11 tagged with Diffuse glioma, H3 G34 mutant itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
Experimental vaccine takes on deadly childhood brain tumors
Disease control OngoingThis phase 1 trial tests a peptide vaccine designed to target a specific mutation (H3K27M) found in certain aggressive brain tumors called diffuse midline gliomas. Fifteen newly diagnosed patients receive the vaccine along with the immunotherapy drug atezolizumab after standard r…
Phase 1 • Sponsor: German Cancer Research Center • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
-
Can a targeted antibody take on glioblastoma?
Disease control OngoingThis phase 1 trial is testing whether amivantamab, an antibody drug given by IV, is safe and tolerable for people with high-grade malignant brain tumors like glioblastoma. The study enrolls about 12 patients with recurrent glioblastoma or certain molecular subtypes. Participants …
Phase 1 • Sponsor: Institute of Cancer Research, United Kingdom • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
-
Experimental vaccine trains immune system to attack deadly brain cancer
Disease control OngoingThis early-phase trial tests a personalized vaccine made from a patient's own white blood cells to treat a rare and aggressive brain tumor called H3 G34-mutant diffuse hemispheric glioma. The vaccine is designed to help the immune system recognize and kill tumor cells. Six adults…
Phase 1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC