Dense deposit disease
MONDO:0019736A histological subtype of C3 glomerulopathy characterized by C3 deposition in renal tissue in the absence or near-absence of immunoglobulin deposits, in a patient with the classic clinical features of glomerulonephritis and electron microscopic findings of highly electron-dense intra-membranous, osmiophilic deposits.
Also known as: Mesangiocapillary glomerulonephritis type 2, membranoproliferative glomerulonephritis type 2, MPGN 2, glomerulonephritis membranoproliferative type 2, membranoproliferative glomerulonephritis type II
8 clinical trials for this condition and its sub-types, 5 tagged with Dense deposit disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
A simple blood test may reveal kidney damage in lupus — no biopsy needed?
Diagnosis Not yet recruitingThis study asks whether levels of uromodulin, a protein in the blood, can indicate the severity of kidney damage in people with lupus nephritis. Researchers will compare uromodulin levels with kidney biopsy results from 90 participants, including those with different classes of l…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Aug 15, 2026 00:00 UTC
-
Can we predict kidney Disease's return after a transplant?
Knowledge-focused Not yet recruitingThis study follows 300 adults in China who have had a kidney transplant due to glomerulonephritis (GN), a type of kidney disease. The goal is to see how often GN comes back after the transplant and what factors might influence that. Participants will be monitored for three years …
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC