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Dengue shock syndrome
MONDO:0000248A dengue disease that involves the most severe form of dengue fever, has material basis in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted by Aedes mosquito bite. The infection has symptom easy bruising, has symptom blood spots, has symptom bleeding gums, and has symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth.
10 clinical trials for this condition and its sub-types, 6 tagged with Dengue shock syndrome itself.
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Could a common steroid tame deadly dengue?
Disease control Recruiting nowThis study is testing whether the steroid dexamethasone can help people with severe dengue. The researchers will give either dexamethasone or a placebo to 200 infected adults in Thailand. They want to see if the drug lowers the death rate and shortens hospital stays.
Sponsor: Chulalongkorn University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Dengue danger linked to leaky gut? new study investigates
Knowledge-focused Recruiting nowThis observational study will enroll 190 hospitalized adults with dengue in Bangladesh to see if a 'leaky gut' — where bacteria and toxins escape the intestines into the blood — is linked to severe disease. Researchers will measure gut leakage markers in blood, perform abdominal …
Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC