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Dedifferentiated chondrosarcoma
MONDO:0005013An aggressive morphologic variant of chondrosarcoma. It is composed of a low grade chondrosarcoma and a high grade non-cartilagenous sarcomatous component. Due to the aggressive nature of the disease, its prognosis is poor.
Also known as: Dedifferentiated chondrosarcoma, DDCHS
2797 clinical trials for this condition and its sub-types, 9 tagged with Dedifferentiated chondrosarcoma itself.
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Can a targeted pill stall advanced sarcomas?
Disease control Recruiting nowThis phase II trial is testing whether abemaciclib, a targeted cancer drug, can slow the growth of advanced bone and soft tissue sarcomas that have a specific alteration in the CDK pathway. Participants take the pill twice daily until their disease worsens or side effects become …
Phase 2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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New daily pill could tame bone sarcomas
Disease control Recruiting nowThis phase 2 trial tests a daily oral drug called zanzalintinib in 70 adults with advanced or metastatic bone sarcomas that cannot be removed by surgery. The study includes four groups based on sarcoma type. Researchers will check if the drug is safe and helps control the cancer.
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Scientists hunt for better ways to diagnose and treat rare bone tumors
Knowledge-focused Recruiting nowThis study looks at 300 people with cartilage tumors, including both benign types and the cancer chondrosarcoma. Researchers are studying genetic changes and molecules called miRNAs to better tell these tumors apart and predict outcomes. The goal is to improve diagnosis and find …
Sponsor: St. Anne's University Hospital Brno, Czech Republic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC