Deafness, unilateral

This study is testing whether a cochlear implant is safe and effective for infants and toddlers who are deaf in one ear. Sixty children will receive the implant and be followed until age 5. Researchers will compare their hearing abilities to children with normal hearing and to th…

This study looks at how well cochlear implants work over three years for people with single-sided deafness or asymmetric hearing loss. Participants receive a cochlear implant system to help them hear better in noisy situations. The goal is to confirm long-term safety and effectiv…

This study is testing the Sentio system, a bone-anchored hearing device, in 25 adolescents aged 12 to 17 with conductive or mixed hearing loss or single-sided deafness. The goal is to see if the device safely improves hearing on the implanted ear. Participants will be followed to…

This study is testing whether a cochlear implant can help children and adults who have severe hearing loss or deafness in one ear but normal hearing in the other. The implant is a device placed behind the ear and under the skin that sends electrical signals to the hearing nerve. …

This study compares two common hearing screening methods—pure-tone audiometry and otoacoustic emissions—in over 13,000 preschool children. The goal is to determine which method is better at identifying hearing loss early, so children can get the help they need to avoid speech and…

This trial tests whether programming a cochlear implant based on the individual's inner ear anatomy (anatomy-based fitting) improves speech understanding in noisy environments and music perception compared to standard programming. The study enrolls adults with single-sided deafne…

This study is testing whether changing the low-frequency settings on a cochlear implant can improve hearing for people who are deaf in one ear but have normal hearing in the other. Twenty-two adults will try four different sound maps during their first month after implant activat…

This study looks at whether a cochlear implant can help children aged 4 to 6 who have severe hearing loss in one ear but normal hearing in the other. The implant is compared to a special hearing aid (CROS or BiCROS). The main goal is to see if the implant improves the child's abi…

This study follows 50 adults aged 18–85 with certain types of hearing loss who either use or could use an FDA-approved bone-anchored hearing device. Over 3 years, researchers will measure changes in memory, attention, and other thinking skills. The goal is to see if treating hear…

This study looks at 20 adults with hearing loss in one ear but a normal-looking eardrum. Doctors want to see how often their best guess about the cause matches what they find during a small ear surgery. The goal is to improve diagnosis and treatment for this tricky condition.

This early-phase study will give IV lidocaine to 40 adults with or without tinnitus and hearing loss, then use fMRI to see how the drug changes brain activity. Participants act as their own control, comparing scans before and after the infusion. The goal is to identify neural net…