Cyanide-induced parkinsonism
MONDO:0017640Cyanide-induced parkinsonism is a rare parkinsonian syndrome due to intoxication which develops in individuals surviving an acute cyanide intoxication episode or due to chronic exposure to small cyanide doses. It presents several weeks after acute exposure with progressive typical clinical features of parkinsonism including bradykinesia, rigidity, dystonia, hypomimia, hypokinetic dysarthria, postural instability and retropulsion but no resting or postural tremor. Brain MRI reveals bilateral lesions in the pallidum, posterior putamen, substantia nigra, subthalamic nucleus, temporal and occipital cortex, and cerebellum.
14 clinical trials for this condition and its sub-types, 0 tagged with Cyanide-induced parkinsonism itself.
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Zapping the brain without surgery: a new hope for Parkinson's?
Disease control By invitation onlyThis study tests a noninvasive technique called temporal interference stimulation (TIS) to see if it can improve motor symptoms in people with Parkinson's disease and related conditions. Participants receive both active and sham stimulation in a random order, with each session la…
Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Massive study tests Blood-Cleaning therapy for poisoning victims
Disease control OngoingThis study looks at whether blood-filtering treatments, such as dialysis or plasma exchange, can help people survive acute poisoning. Researchers will compare over 5,000 poisoned patients who received these treatments with those who did not. The goal is to see if the treatments i…
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Heart scan may spot hidden brain disease
Diagnosis By invitation onlyThis study tests whether a special heart scan using a radioactive drug called 123I-MIBG can help identify Lewy body disease, a type of dementia that also affects movement and sleep. Researchers will compare scan results with clinical diagnoses in 50 people who have conditions lik…
Phase 4 • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Aug 01, 2026 00:00 UTC
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New PET scan could slash radiation by 100x
Diagnosis By invitation onlyThis study tests a new PET imaging technique that uses 10 to 100 times less radiation than standard scans. Researchers will inject 200 healthy volunteers and patients with a radioactive tracer and use a high-sensitivity scanner to see if image quality remains good enough for dete…
Phase 2 • Sponsor: Akiva Mintz • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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Scientists hunt for clues to diagnose Parkinson's earlier
Knowledge-focused OngoingThis study aims to identify biomarkers—biological clues in the body—that can help distinguish between Parkinson's disease and similar conditions like progressive supranuclear palsy and multiple system atrophy. Researchers will follow people with early-stage parkinsonism and healt…
Sponsor: Non-profit organization for scientific research in Parkinson's disease and related disorders • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC