Cushing disease due to pituitary adenoma
MONDO:0009050A form of adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome, an endogenous Cushing syndrome (CS), characterized by chronic over-secretion of adrenocorticotropic hormone (ACTH) due to a pituitary corticotroph adenoma.
Also known as: ACTH producing pituitary adenoma, Cushing disease, Cushing disease, pituitary, Cushing's disease, PITA4, corticotroph pituitary adenoma, pituitary adenoma 4, ACTH-secreting, pituitary adenoma 4, ACTH-secreting, somatic
1545 clinical trials for this condition and its sub-types, 23 tagged with Cushing disease due to pituitary adenoma itself.
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New drug shows promise for cortisol disorder
Disease control CompletedThis study tested an experimental drug called SPI-62 in 26 adults with Cushing's syndrome caused by a non-adrenal tumor. The goal was to see if SPI-62 could lower cortisol levels safely. Participants received either SPI-62 or a placebo for 24 weeks, with an option to continue lon…
Phase 2 • Sponsor: Sparrow Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New PET/MRI scan could spot elusive brain tumors in Cushing's patients
Diagnosis CompletedThis study tested whether a special scan called [11C]-Methionine PET/MRI can better locate tiny pituitary tumors that cause Cushing's disease. Standard MRI often misses these tumors, leading to risky exploratory surgery. The study involved 33 adults with confirmed Cushing's disea…
Sponsor: Hospices Civils de Lyon • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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New study tracks hidden heart and bone risks in Cushing's disease
Knowledge-focused CompletedThis study followed 80 people with newly diagnosed Cushing's disease for three years to see how the disease affects the heart, bones, metabolism, and quality of life. Researchers used blood tests, heart scans, bone density tests, and questionnaires to track complications before a…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Virtual reality test reveals hidden memory damage in cured Cushing's patients
Knowledge-focused CompletedThis study looked at whether people who have been cured of Cushing's disease for at least a year still have memory problems. Researchers used a special virtual reality test to check memory, along with standard tests. The goal was to better understand these lasting effects and imp…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC