Creutzfeldt Jacob disease
MONDO:0005357A rare transmittable degenerative disorder of the brain caused by prions. Morphologically it is characterized by spongiform degeneration of the cerebral and cerebellar cortex. Signs and symptoms include sleep disturbances, personality changes, aphasia, ataxia, muscle atrophy and weakness, visual loss, and myoclonus. It usually leads to death within a year from the onset of the disease.
Also known as: CJD, CJD (Creutzfeldt Jakob disease), Creutzfeldt Jakob Disease, Creutzfeldt-Jacob disease, Jakob-Creutzfeldt disease, classic Creutzfeldt-Jakob disease, Creutzfeldt-Jakob disease
7 clinical trials for this condition and its sub-types, 4 tagged with Creutzfeldt Jacob disease itself.
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Sub-types of Creutzfeldt Jacob disease
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Inherited Creutzfeldt-Jakob disease 5 trials
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Acquired Creutzfeldt-Jakob disease 0 trials
2 sub-types
- Iatrogenic Creutzfeldt-Jakob disease 0 trials
- Variant Creutzfeldt-Jakob disease 0 trials
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Sporadic Creutzfeldt-Jakob disease 0 trials
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Can a One-Page guide spark better End-of-Life talks for dementia patients?
Knowledge-focused OngoingThis study tests a short guide called the 'Jumpstart Guide' to help doctors have better conversations with dementia patients and their families about healthcare goals. Over 1,800 patients and their caregivers are taking part. Researchers will compare whether those whose doctors u…
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Sep 21, 2026 14:00 UTC
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Looking back to see ahead: study aims to spot CJD faster
Knowledge-focused By invitation onlyThis study looks back at the medical records of 150 people diagnosed with Creutzfeldt-Jakob disease (CJD), a rare and fast-moving brain disorder. Researchers will examine symptoms, blood tests, spinal fluid, brain scans, and EEG results to find patterns that could help doctors di…
Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC