CREST syndrome

MONDO:0019563

CREST syndrome is a subtype of limited cutaneous systemic sclerosis (lcSSc) whose name is an acronym for the cardinal clinical features of the syndrome: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia.

Also known as: lcSSc, calcinosis-Raynaud phenomenon-esophageal involvement-sclerodactyly-telangiectasia syndrome, limited cutaneous Systemic Scleroderma, limited cutaneous Systemic sclerosis, CRST syndrome, CRST syndromes, calcinosis - Raynaud phenomenon - esophageal involvement - sclerodactyly - telangiectasia, calcinosis Raynaud phenomenon sclerodactyly telangiectasia

36 clinical trials for this condition and its sub-types, 0 tagged with CREST syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Syndromic disease (7133) ↑ Limited cutaneous systemic sclerosis (2)

Including sub-types (36) Tagged with CREST syndrome (0)

Trials to join now! 13 Not yet recruiting 9 Not yet finished but already full! 5 Completed 8 Terminated 1

Biopsy tolerance study ends early – what we know

Knowledge-focused Stopped early

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

Sponsor: University Hospital, Brest • Aim: Knowledge-focused

Last updated Jun 28, 2026 00:00 UTC

CREST syndrome

Where it sits in the disease tree

Biopsy tolerance study ends early – what we know