Coronary restenosis

This pilot study tests a new type of stent—a drug-coated, spur-shaped device—as a primary treatment for in-stent restenosis, where a previously placed coronary artery narrows again. The trial enrolls up to 9 adults with this condition to see if the device is safe in the short ter…

This study looked at 108 people whose heart stents had narrowed again after being placed. Doctors tested three different devices: two types of drug-coated balloons and one new stent. The goal was to see which one works best to keep the artery open and prevent future heart problem…

This study tested a special balloon coated with the drug everolimus in 51 people whose previously placed heart stents had become blocked again. The balloon is inflated inside the artery to deliver the drug directly to the blockage, aiming to keep the artery open. The main goals w…

This study tested a new balloon catheter called SINOMED CBC for treating narrowed coronary arteries. It involved 136 patients with stable or unstable angina or evidence of heart muscle ischemia. The device was compared to a standard balloon catheter to see if it was as safe and e…

This study looked at how well the Xience Sierra drug-coated stent works in a broad group of heart disease patients, including those with diabetes or prediabetes. Over 1,700 participants received the stent during a routine procedure to open blocked arteries. Researchers tracked he…

This study tested a special balloon coated with sirolimus, a drug that helps prevent arteries from narrowing again after angioplasty. It included 110 adults with stable or unstable coronary artery disease who had long blockages (at least 25 mm) in their heart arteries. The main g…

This study tested whether a parasternal block—an injection of the numbing drug ropivacaine into the chest wall—could reduce the amount of anesthetic needed to keep heart rate and blood pressure stable during coronary artery bypass surgery. Thirty-five patients were randomly assig…

This completed study looked at 1000 people who had a coronary stent placed to see if a score based on insulin resistance could predict whether the stent would narrow again (restenosis). Researchers measured insulin resistance using routine blood tests and checked for restenosis w…

This study involved 150 people with completely blocked heart arteries who had a special procedure called STAR. Researchers wanted to find the best time to place a stent afterward—either 5-7 weeks or 12-14 weeks later. The goal was to see which timing leads to a more successful st…