Corneal ulcer

This trial tests whether injecting natural killer (NK) cells into the eye can help people with refractory Mooren's ulcer, a painful and recurring corneal condition. Six participants will receive the cell injection and be followed for 48 weeks to see if it improves corneal thickne…

This study tests a special hydrogel that acts like a glue to hold eye tissues together during surgery, avoiding the need for stitches. Stitches can cause pain, swelling, and scarring, but this gel uses light to bond quickly and gently. The trial will include 20 people with cornea…

This early study tests a 3D-printed human collagen implant in 4 people with severe corneal melting, a condition where the eye's clear front layer thins and can perforate. The implant is placed on the eye to reinforce the cornea and prevent vision loss. The main goal is to check i…

This study checks if a special thinking test (MoCA Blind) can find memory or thinking problems after cornea surgery. It includes 200 adults with cornea disease who will take the test before and 90 days after surgery. The goal is to give doctors a better way to spot these issues i…

This phase 2 trial tests whether adding a steroid eye drop (fluorometholone) to standard antibiotic treatment improves vision at 3 months in people with bacterial corneal ulcers. About 174 adults with mild to severe ulcers will be randomly assigned to get either the steroid plus …