Congenital merosin-deficient muscular dystrophy 1A
MONDO:0011925Congenital muscular dystrophy type 1A (MCD1A) belongs to a group of neuromuscular disorders with onset at birth or infancy characterized by hypotonia, muscle weakness and muscle wasting.
Also known as: CMD1A, LAMA2 congenital muscular dystrophy, MDC1A, congenital merosin-deficient muscular dystrophy type 1A, congenital muscular dystrophy caused by mutation in LAMA2, congenital muscular dystrophy due to laminin alpha2 deficiency, merosin-deficient congenital muscular dystrophy type 1A, merosin-negative congenital muscular dystrophy
8 clinical trials for this condition and its sub-types, 3 tagged with Congenital merosin-deficient muscular dystrophy 1A itself.
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New study tracks toddlers with rare muscle disease to prep for future treatments
Knowledge-focused Recruiting nowThis study watches how children under 5 with LAMA2-related muscular dystrophy move and develop over two years. Researchers will test muscle function, swallowing, breathing, and collect blood samples. The goal is to learn more about the disease so future treatments can be tested e…
Sponsor: Nationwide Children's Hospital • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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A protein clue in the fight against muscular dystrophy?
Knowledge-focused Recruiting nowThis study looks at whether levels of a protein called HMGB1 are different in people with LAMA2-related muscular dystrophy, a condition that causes severe muscle weakness. Researchers will measure HMGB1 in blood and muscle samples already collected from about 25 patients. The goa…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Swiss launch major registry to track rare muscle diseases
Knowledge-focused Recruiting nowThis study is a registry that collects health information from people in Switzerland who have neuromuscular disorders like SMA, DMD, BMD, and others. It aims to track symptoms, treatments, and outcomes over time to help researchers and doctors improve care. No new treatments are …
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC