Congenital heart malformation
MONDO:0019512A disease that has its basis in the disruption of heart development.
Also known as: congenital heart malformation, disorder of heart development, heart development disease, congenital non-syndromic heart malformation, rare congenital non-syndromic heart malformation
154 clinical trials for this condition and its sub-types, 3 tagged with Congenital heart malformation itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Congenital heart malformation
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Congenital anomaly of the great arteries 1 trial · 72 incl. sub-types
15 sub-types
- Aortic arch defects 1 trial · 28 incl. sub-types Sub-types →
- Aneurysm or dilatation of ascending aorta 27 trials
- Congenital pulmonary valve stenosis 2 trials · 7 incl. sub-types Sub-types →
- Pulmonary branch stenosis 5 trials
- Congenital pulmonary veins atresia or stenosis 4 trials Sub-types →
- Absence of the pulmonary artery 1 trial
- Aortic arch interruption 0 trials
- Aorto-ventricular tunnel 0 trials Sub-types →
- Congenital patent ductus arteriosus aneurysm 0 trials
- Fixed subaortic stenosis 0 trials Sub-types →
- Idiopathic pulmonary artery dilatation 0 trials
- Premature closure of the arterial duct 0 trials
- Primary pulmonary vein stenosis 0 trials
- Pulmonary artery hypoplasia 0 trials
- Scimitar syndrome 0 trials
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Conotruncal heart malformations 1 trial · 40 incl. sub-types
8 sub-types
- Tetralogy of fallot 33 trials
- Persistent truncus arteriosus 8 trials Sub-types →
- Double outlet right ventricle 2 trials · 3 incl. sub-types Sub-types →
- Pulmonary atresia with ventricular septal defect 1 trial
- Abnormal origin of the pulmonary artery 0 trials Sub-types →
- Congenital aortopulmonary window 0 trials
- Double outlet left ventricle 0 trials
- Pulmonary valve agenesis 0 trials Sub-types →
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Univentricular cardiopathy 14 trials · 37 incl. sub-types
3 sub-types
- Univentricular heart 21 trials Sub-types →
- Hypoplastic left heart syndrome 9 trials Sub-types →
- Hypoplastic right heart syndrome 0 trials · 4 incl. sub-types Sub-types →
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Transposition of the great arteries 10 trials · 11 incl. sub-types
3 sub-types
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Congenital left-sided heart lesions 0 trials · 9 incl. sub-types
1 sub-type
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Coronary artery congenital malformation 3 trials · 4 incl. sub-types
9 sub-types
- Aortopulmonary coronary arterial course 1 trial
- Stenosis or atrophy of the coronary ostium 1 trial
- Abnormal number of coronary ostia 0 trials
- Anomalous left coronary artery from the pulmonary artery 0 trials
- Congenital coronary artery aneurysm 0 trials
- Coronary arterial fistulas 0 trials
- Coronary artery intramyocardial course 0 trials
- Intramural coronary arterial course 0 trials
- Malposition of the coronary ostium 0 trials
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Congenital mitral malformation 0 trials · 2 incl. sub-types
2 sub-types
- Congenital mitral valve insufficiency and/or stenosis 1 trial · 2 incl. sub-types Sub-types →
- Cleft mitral valve 0 trials Sub-types →
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Visceral heterotaxy 1 trial
19 sub-types
- Dextrocardia 1 trial
- Situs inversus 1 trial Sub-types →
- Heterotaxy, visceral, 1, X-linked 0 trials
- Heterotaxy, visceral, 10, autosomal, with male infertility 0 trials
- Heterotaxy, visceral, 11, autosomal, with male infertility 0 trials
- Heterotaxy, visceral, 12, autosomal 0 trials
- Heterotaxy, visceral, 13, autosomal 0 trials
- Heterotaxy, visceral, 14, autosomal 0 trials
- Heterotaxy, visceral, 2, autosomal 0 trials
- Heterotaxy, visceral, 3, autosomal 0 trials
- Heterotaxy, visceral, 4, autosomal 0 trials
- Heterotaxy, visceral, 5, autosomal 0 trials
- Heterotaxy, visceral, 6, autosomal 0 trials
- Heterotaxy, visceral, 7, autosomal 0 trials
- Heterotaxy, visceral, 8, autosomal 0 trials
- Heterotaxy, visceral, 9, autosomal, with male infertility 0 trials
- Laterality defects, autosomal dominant 0 trials
- Levocardia 0 trials
- Right atrial isomerism 0 trials
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Laubry-Pezzi syndrome 0 trials
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Atrial septal aneurysm 0 trials
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Cardiac diverticulum 0 trials
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Congenital Gerbode defect 0 trials
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Congenital acardia 0 trials
1 sub-type
- Holoacardius amorphus 0 trials
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Congenital pericardium anomaly 0 trials
3 sub-types
- Congenital complete agenesis of pericardium 0 trials
- Congenital partial agenesis of pericardium 0 trials
- Pleuro-pericardial cyst 0 trials
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Congenital right-sided heart lesions 0 trials
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Criss-cross heart 0 trials
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Ectasia of the left appendage 0 trials
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Ectopia cordis 0 trials
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Interventricular septum aneurysm 0 trials
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Mesocardia 0 trials
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Triatrial heart 0 trials
2 sub-types
- Cor triatriatum dexter 0 trials
- Cor triatriatum sinister 0 trials
Most studied deeper sub-types
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Experimental cell therapy takes on stubborn autoimmune diseases
Disease control Stopped earlyThis early study tested a new cell therapy called LUCAR-G79 in just 3 adults with severe autoimmune diseases that did not respond to standard treatments. The therapy uses specially engineered immune cells to target and potentially calm the overactive immune system. The main goals…
Phase 1 • Sponsor: Nanjing Legend Biotech Co. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a brain zap and computer game sharpen aging minds?
Symptom relief Stopped earlyThis study tested whether combining a computer-based speed-of-processing training with a gentle electrical brain stimulation (alpha-tACS) could improve how quickly people with mild cognitive impairment process visual information. The trial planned to enroll 40 adults aged 65 and …
Sponsor: Portucalense University • Aim: Symptom relief
Last updated Jun 26, 2026 16:29 UTC
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Dopamine may unclog lymphatic system in rare heart complication
Knowledge-focused Stopped earlyThis study looks at whether dopamine can improve lymph flow in people who developed protein-losing enteropathy (PLE) after Fontan surgery for single-ventricle heart disease. PLE is a serious complication where proteins leak into the gut, possibly due to poor lymphatic function. R…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Wireless heart monitor for infants tested, but study ends early
Knowledge-focused Stopped earlyThis study aimed to see if a wireless sensor could collect health information from babies with heart defects at home, replacing wired devices. Only 2 infants were enrolled before the study was stopped. The goal was to understand if the wireless device was easy to use and worked w…
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC