Combined pituitary hormone deficiencies, genetic form
MONDO:0013099Congenital hypopituitarism is characterized by multiple pituitary hormone deficiency, including somatotroph, thyrotroph, lactotroph, corticotroph or gonadotroph deficiencies, due to mutations of pituitary transcription factors involved in pituitary ontogenesis. Congenital hypopituitarism is rare compared with the high incidence of hypopituitarism induced by pituitary adenomas, transsphenoidal surgery or radiotherapy.
Also known as: familial congenital hypopituitarism, genetic hypopituitarism, multiple pituitary hormone deficiencies, genetic forms, pituitary hormone deficiency, combined, combined pituitary hormone deficiencies, genetic forms, familial hypopituitarism
43 clinical trials for this condition and its sub-types, 1 tagged with Combined pituitary hormone deficiencies, genetic form itself.
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Sub-types of Combined pituitary hormone deficiencies, genetic form
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7 sub-types
- Isolated growth hormone deficiency type IA 0 trials
- Isolated growth hormone deficiency type IB 0 trials
- Isolated growth hormone deficiency type II 0 trials
- Isolated growth hormone deficiency type III 0 trials Sub-types →
- Isolated growth hormone deficiency, type 4 0 trials
- Isolated growth hormone deficiency, type 5 0 trials
- Short stature due to growth hormone qualitative anomaly 0 trials
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Panhypopituitarism 2 trials
2 sub-types
- Panhypopituitarism, X-linked 0 trials
- Pituitary hormone deficiency, combined, 2 0 trials
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Septooptic dysplasia 1 trial
2 sub-types
- Congenital absence of septum pellucidum 0 trials
- Pagon stephan syndrome 0 trials
Most studied deeper sub-types
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Daily pill may replace growth hormone shots for children
Disease control Not yet recruitingThis study evaluates the long-term safety of an oral medication called LUM-201 for children with growth hormone deficiency (GHD). Children who completed a prior 12-month trial can receive LUM-201 daily for up to 36 additional months. The goal is to see if the pill is safe and tol…
Phase 3 • Sponsor: Lumos Pharma • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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New Long-Acting growth hormone shot could mean fewer needles for kids
Disease control Not yet recruitingThis study tests a new medicine called GenSci134, a long-acting growth hormone, in 128 children with growth hormone deficiency (GHD). The goal is to find the best dose and see if it is safe and helps children grow taller. In the first part, children get one shot of GenSci134; in …
Phase 1/2 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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300 belgian kids to help unlock growth Hormone's metabolic secrets
Knowledge-focused Not yet recruitingThis study will follow 300 Belgian children with growth hormone deficiency for three years to see how their bodies respond to daily or weekly growth hormone shots. Researchers will measure growth, weight, blood sugar, fats, and other health markers. The goal is to understand whic…
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC