Classic familial adenomatous polyposis
MONDO:0021055Familial adenomatous polyposis (FAP) is characterized by the development of hundreds to thousands of adenomas in the rectum and colon during the second decade of life.
Also known as: FAP, Familial Adenomatous Polyposis, adenomatous polyposis coli, classic FAP, classic familial adenomatous polyposis, colorectal adenomatous polyposis, familial adenomatous polyposis, familial adenomatous polyposis coli
65 clinical trials for this condition and its sub-types, 33 tagged with Classic familial adenomatous polyposis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Classic familial adenomatous polyposis
-
Gardner syndrome 1 trial
-
Turcot syndrome with polyposis 0 trials
-
Can an experimental drug stop polyps from coming back in a rare inherited condition?
Disease control Not yet recruitingThis phase 1b trial tests an experimental drug called ST316 in adults with familial adenomatous polyposis (FAP) who have already had their colon removed but still develop new polyps. The study aims to see if ST316 is safe and can reduce the number and size of polyps that grow bac…
Phase 1 • Sponsor: Sapience Therapeutics • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
-
Could a common drug curb polyps in teens with rare genetic condition?
Disease control Not yet recruitingThis study tests two low doses of rapamycin, a drug usually used to prevent organ rejection, in 25 teenagers (ages 12-17) with familial adenomatous polyposis (FAP), a genetic condition that causes many colon polyps and raises cancer risk. The main goal is to see if the drug is sa…
Phase 2 • Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC