Circadian rhythm sleep disorder, delayed sleep phase type

This study follows 3,400 adults referred to a sleep clinic for insomnia or circadian rhythm sleep disorders. Participants receive standard care—such as light therapy, melatonin, and blue-light-blocking glasses—and track their progress through questionnaires and sleep diaries. The…

This study tests whether using a bright blue light device for 15-30 minutes each morning can slow the progression of idiopathic scoliosis in children aged 10-15 who are night owls. The trial will enroll 120 participants and follow them for 6 months, measuring spine curve changes …

This study tests whether wearing blue-blocking glasses at night can help teenagers (ages 12-18) with insomnia or delayed sleep phase disorder who are already receiving psychiatric care. Forty participants will wear the glasses or use real darkness for one week. The goal is to see…

This study tests whether the drug Lemborexant helps people with delayed sleep phase syndrome fall asleep faster at their desired bedtime. Fifteen adults will take either the drug or a placebo nightly for up to 2 years, tracking sleep with logs and a wrist monitor. The goal is to …

This study tests whether a low-dose melatonin pill (0.5 mg) combined with a behavioral sleep program can shift the body's internal clock earlier and improve mood in people with bipolar disorder who are night owls. Fifty participants will either get melatonin plus sleep therapy or…

This study tests whether a sleep-focused therapy can improve depression in teenagers whose body clocks are out of sync with their wake-up time. Researchers will enroll 200 adolescents with depression and delayed sleep phase. The therapy aims to realign their internal circadian rh…

This study aims to understand what causes delayed sleep wake phase disorder (DSWPD), a condition where people's sleep times are shifted later. Researchers will compare 66 participants with DSWPD to healthy controls by measuring body temperature, melatonin, and thinking ability du…

This study looks at how the pupils of people with Delayed Sleep-Wake Phase Disorder react to light. Researchers want to see if there are differences in light sensitivity and whether a single dose of citalopram (a serotonin-boosting drug) can increase melatonin suppression during …