Chronic bronchitis
MONDO:0005607A type of chronic obstructive pulmonary disease characterized by chronic inflammation in the bronchial tree that results in edema, mucus production, obstruction, and reduced airflow to and from the lung alveoli. The most common cause is tobacco smoking. Signs and symptoms include coughing with excessive mucus production, and shortness of breath.
Also known as: bronchitis, chronic
36 clinical trials for this condition and its sub-types, 23 tagged with Chronic bronchitis itself.
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New COPD drug shows promise in cutting lung Flare-Ups
Disease control OngoingThis study tests a new drug called verekitug in 666 people with moderate-to-severe COPD, a long-term lung disease that makes breathing hard. The goal is to see if it can reduce serious flare-ups and improve lung function compared to a placebo. Participants must be current or form…
Phase 2 • Sponsor: Upstream Bio Inc. • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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COPD patients may breathe easier by switching to heated tobacco
Symptom relief OngoingThis study looks at whether people with COPD and chronic bronchitis who switch from regular cigarettes to a tobacco heating system feel better and breathe easier. About 290 adults aged 40 and older who have smoked for at least 10 years will take part. Researchers will measure cou…
Sponsor: Philip Morris Products S.A. • Aim: Symptom relief
Last updated Sep 02, 2026 00:00 UTC
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Massive italian study aims to uncover what really affects COPD survival
Knowledge-focused By invitation onlyThis large real-world study will follow 10,000 Italian patients with COPD to see how their treatments, flare-ups, and other health conditions affect their risk of death. Researchers will collect data on medications, lung function, and heart problems over time. The goal is to bett…
Sponsor: University of Milan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Massive COPD study aims to unlock secrets of lung disease
Knowledge-focused OngoingThis study follows nearly 3,000 people with COPD (a chronic lung disease) over several years to understand how the disease progresses and what factors influence it. Researchers measure lung function, analyze mucus, and track environmental exposures like air pollution. The goal is…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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COPDGene: unlocking the genetic secrets of lung disease in smokers
Knowledge-focused OngoingThis study is looking at over 10,000 smokers to find out if certain genes make some people more likely to develop COPD, a serious long-term lung disease. Participants are having their lung function tested and getting chest CT scans. The goal is to understand why some smokers get …
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:03 UTC