Chronic bronchitis
MONDO:0005607A type of chronic obstructive pulmonary disease characterized by chronic inflammation in the bronchial tree that results in edema, mucus production, obstruction, and reduced airflow to and from the lung alveoli. The most common cause is tobacco smoking. Signs and symptoms include coughing with excessive mucus production, and shortness of breath.
Also known as: bronchitis, chronic
36 clinical trials for this condition and its sub-types, 23 tagged with Chronic bronchitis itself.
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Can a new biologic drug prevent COPD Flare-Ups?
Disease control Recruiting nowThis phase 2 trial tests whether galvokimig, an experimental biologic drug, can reduce the number of moderate-to-severe COPD flare-ups in people with chronic bronchitis. About 400 adults aged 40 to 80 with moderate-to-severe COPD will receive either galvokimig or a placebo as an …
Phase 2 • Sponsor: UCB Biopharma SRL • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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COPD study tests two education programs to keep patients out of hospital
Symptom relief Recruiting nowThis study compares two COPD self-management education programs: a self-guided booklet and a counselor-led phone program. Researchers want to see which approach better reduces hospitalizations and improves quality of life. 448 adults with COPD who have been hospitalized in the pa…
Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Electric pulses to the lungs: a new hope for COPD cough?
Symptom relief Recruiting nowThis study tests a device that delivers gentle electric pulses to the airways to reduce chronic bronchitis symptoms in adults with COPD. About 210 participants will either receive the real treatment or a sham procedure. The goal is to see if the treatment improves breathing and q…
Sponsor: Suzhou Hengruihongyuan Medical Technology Co. LTD • Aim: Symptom relief
Last updated Jun 26, 2026 12:32 UTC
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Scientists hunt for COPD genes in young patients
Knowledge-focused Recruiting nowThis study aims to find the genes that make some people develop severe COPD at a young age, even if they smoke. Researchers will collect DNA and health information from 2,000 participants with early-onset COPD. The goal is to understand why some people are more prone to this lung…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Scientists build genetic database to crack Emphysema's secrets
Knowledge-focused Recruiting nowThis study is creating a registry of people with emphysema to collect DNA, lung function tests, and medical information. Researchers hope to use this data to better understand the disease and develop new therapies. The registry will also help identify volunteers for future resear…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC