Choroideremia

MONDO:0010557

Choroideremia (CHM) is an X-linked chorioretinal dystrophy characterized by progressive degeneration of the choroid, retinal pigment epithelium (RPE) and retina.

Also known as: CHM, Tapetochoroidal dystrophy, choroideremia, progressive choroidal atrophy, TCD, Tapetochoroidal dystrophy, progressive, choroidal sclerosis, progressive tapetochoroidal dystrophy

31 clinical trials for this condition and its sub-types, 6 tagged with Choroideremia itself.

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Where it sits in the disease tree

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Part of

↑ Neurovascular disorder (4196) ↑ Inherited retinal dystrophy (510) ↑ X-linked disease (323) ↑ Optic choroid disorder (26)

Sub-types of Choroideremia

Choroideremia hypopituitarism 0 trials
Total central choroidal atrophy 0 trials

Including sub-types (31) Tagged with Choroideremia (6)

Trials to join now! 14 Not yet recruiting 3 Not yet finished but already full! 1 Completed 11 Terminated 2

Gene therapy injection aims to restore sight in rare eye diseases

Disease control Ongoing

This early-phase trial tests a single injection of a gene therapy called RTx-015 in 10 adults with retinitis pigmentosa or choroideremia, two inherited conditions that cause vision loss. The therapy delivers a gene that makes retinal cells produce a light-sensitive protein, poten…

Phase 1 • Sponsor: Ray Therapeutics, Inc. • Aim: Disease control

Last updated Jun 27, 2026 09:07 UTC

Choroideremia

Where it sits in the disease tree

Gene therapy injection aims to restore sight in rare eye diseases