Childhood kidney cell carcinoma

This early-phase trial tests two drugs together—MK-2206 and hydroxychloroquine—in people with advanced solid tumors, melanoma, kidney, or prostate cancer. The goal is to find the safest dose and see how the combination affects cancer cell growth. About 62 participants will take b…

This early-stage trial is testing whether amivantamab, a drug that targets specific proteins on cancer cells, can be given as a shot under the skin instead of through an IV. About 158 adults with advanced solid tumors (like lung or head and neck cancers) will receive different do…

This pilot study tested whether adding low-dose radiation (brachytherapy) to standard immunotherapy could help shrink tumors in people with advanced melanoma, kidney cancer, or urothelial cancer. Only 5 participants were enrolled, and the main goal was to see how many responded t…

This study tests a new type of MRI that uses a natural substance (pyruvate) to see how active a kidney tumor is. The goal is to find out if the scan can tell the difference between harmless tumors, slow-growing cancers, and fast-growing cancers without needing a needle biopsy. Ab…

This trial tests whether one month of prehabilitation, including a health assessment, home exercise, and smoking cessation support, helps adults aged 65 and older recover more quickly from kidney tumor surgery. Half the participants receive this program before surgery, while the …

This study looks at whether a 12-week survivorship program for men with advanced prostate, kidney, bladder, testicular, or penile cancer can be successfully added to their regular follow-up care. Researchers will measure how feasible and acceptable the program is using questionna…