Childhood acute myeloid leukemia
MONDO:0004996Acute myeloid leukemia occurring in childhood.
Also known as: acute myeloid leukaemia (AML), acute myeloid leukemia (AML), acute myeloid leukaemia of childhood, acute myeloid leukemia of childhood, childhood AML, childhood acute granulocytic leukaemia, childhood acute granulocytic leukemia, childhood acute myeloblastic leukaemia
3267 clinical trials for this condition and its sub-types, 24 tagged with Childhood acute myeloid leukemia itself.
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Precision radiation may boost stem cell transplant success in tough leukemias
Disease control OngoingThis study tests a precise radiation method called total marrow and lymphoid irradiation (TMLI) given with two chemotherapy drugs (etoposide and cyclophosphamide) before a donor stem cell transplant. The goal is to safely deliver higher radiation doses to the bone marrow to wipe …
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Promising leukemia drug tested as maintenance after transplant in kids
Disease control CancelledThis study was designed to test the safety and best dose of the drug revumenib in children and young adults with certain types of leukemia (ALL, AML, or mixed phenotype) after they have received a stem cell transplant. The goal was to see if revumenib could help prevent the cance…
Phase 1 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New drug combo shows promise for rare childhood leukemia
Disease control OngoingThis study tests whether adding a drug called selinexor to standard chemotherapy can help children with a specific, high-risk form of acute myeloid leukemia (NUP98-positive AML). Ten children will receive the combination during their first two rounds of treatment. The goal is to …
Phase 2 • Sponsor: The Children's Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New brain scan may predict chemo brain in young leukemia patients
Knowledge-focused PausedThis study tests a quick, non-invasive brain scan called Magnetic Resonance Fingerprinting (MRF) in children and young adults with acute leukemia. The goal is to see if the scan can detect early brain changes caused by chemotherapy. Participants also take a fun, game-like memory …
Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC