Chiari malformation type I
MONDO:0007316Arnold-Chiari malformation type I is a central nervous system malformation characterized by caudal displacement of the cerebellar tonsils exceeding 5mm below the foramen magnum with or without syringomyelia. Symptoms vary in onset and severity and include suboccipital headache, neck pain, vertigo, tinnitus, ocular symptoms (diplopia, blurred vision, photofobia, nystagmus), lower cranial nerve signs, cerebellar ataxia, and spasticity. Some affected individuals can be asymptomatic.
Also known as: Arnold-Chiari malformation type 1, Arnold-Chiari malformation type I, Chiari malformation type 1, Chiari malformation type I, Chiari malformation type 1 with syringomyelia, Cm1, Cm1 with syringomyelia
10 clinical trials for this condition and its sub-types, 9 tagged with Chiari malformation type I itself.
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Can MRI scans reveal the hidden fluid dynamics behind chiari malformation?
Knowledge-focused Recruiting nowThis study uses special MRI scans to measure the flow of cerebrospinal fluid and blood in the brain and spine of people with Chiari malformation. The goal is to see how these flows differ between people with symptoms and those without. Researchers will compare these measurements …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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Massive study aims to predict brain surgery success
Knowledge-focused Recruiting nowThis study is gathering information from 4500 people who have or will have brain surgery for conditions like aneurysms, tumors, epilepsy, and Parkinson's disease. The goal is to find patterns that help doctors predict how well someone will recover. By standardizing how outcomes a…
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC