CHEK2-related cancer predisposition
MONDO:0700271Hereditary cancer predisposition due to variation(s) in the CHEK2 gene. Pathogenic germline variation in CHEK2 confers an autosomal dominant predisposition to tumor formation at multiple primary sites, including breast cancer and prostate cancer.
39 clinical trials for this condition and its sub-types, 7 tagged with CHEK2-related cancer predisposition itself.
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New scan may improve cancer detection for men with inherited risk
Diagnosis Recruiting nowThis study compares a new PET-CT scan (FCH-PET-CT) to standard imaging (bone scan and MRI/CT) to see which better finds cancer that has spread outside the pelvis in men with prostate cancer and specific DNA repair gene mutations. About 50 men with these mutations will be enrolled…
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
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Can digital tools make cancer genetic counseling more effective?
Knowledge-focused Recruiting nowThis study looks at two new approaches to cancer genetic counseling. The first helps doctors reach out to family members who may have inherited a cancer-related gene change, making it easier for them to get tested. The second uses an online portal to keep patients and their docto…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC