Chagas disease
MONDO:0001444A parasitic infection caused by Trypanosoma cruzi. It is transmitted by insect bites. It is characterized by an acute and chronic phase; in the acute phase patients may have fever, malaise, and swelling at the site of the insect bite. In the chronic phase patients develop hepatosplenomegaly, lymphadenopathy, cardiomyopathy and arrhythmias.
Also known as: Chagas disease, Chagas' disease, Trypanosoma cruzi caused disease or disorder, Trypanosoma cruzi disease or disorder, Trypanosoma cruzi infectious disease, infection by trypanosoma cruzi, Chagas-mazza disease, infection caused by trypanosoma cruzi
13 clinical trials for this condition and its sub-types, 12 tagged with Chagas disease itself.
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Prison walls may not stop Animal-Borne diseases
Knowledge-focused Not yet recruitingResearchers are measuring how often five animal-borne infections appear among inmates at the French Guiana Correctional Facility. The study follows newly arrived adults for up to 12 months, testing for Q fever, leptospirosis, Chagas disease, histoplasmosis, and toxoplasmosis. The…
Sponsor: Centre Hospitalier de Cayenne • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC
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Chagas drug safety in pregnancy under scrutiny in new 10-year study
Knowledge-focused Not yet recruitingThis study follows 50 pregnant women with Chagas disease who take or have taken nifurtimox, to see if the drug causes harm to the baby or mother. Researchers will track birth defects, pregnancy outcomes, and infant health up to 12 months old. The goal is to collect safety data, n…
Sponsor: Bayer • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC