Cervical squamous intraepithelial neoplasia
MONDO:0042491A neoplastic process that affects the squamous epithelium of the cervix. It is classified as cervical squamous intraepithelial neoplasia 1, 2, or 3, according to the degree of squamous cell maturation and cellular atypia, and the number of mitotic figures.
Also known as: CIN, cervical sil, cervical squamous intraepithelial lesion, cervical squamous intraepithelial neoplasia, cervix squamous intraepithelial lesion, cervix uteri sil, cervix uteri squamous intraepithelial lesion, squamous intraepithelial lesion of cervix
1478 clinical trials for this condition and its sub-types, 28 tagged with Cervical squamous intraepithelial neoplasia itself.
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CRISPR zaps HPV in cervical lesions: first human test begins
Disease control Stopped earlyThis early study tests a new CRISPR gene therapy (BD114) in 12 women with high-grade cervical lesions caused by HPV-16. The therapy is injected directly into the lesion to disable the virus's cancer-causing genes. The main goals are to check safety and see if the lesions clear up…
Early phase 1 • Sponsor: Shanghai BDgene Co., Ltd. • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Cervical lesion drug trial halted early
Disease control Stopped earlyThis study tested a vaginal insert called ABI-2280 in women with cervical precancerous lesions (CIN). The goal was to see if it was safe and could help clear the abnormal cells. The trial was stopped early, so we don't have full results. It involved 44 women aged 25-55 who used t…
Phase 1/2 • Sponsor: Antiva Biosciences • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC