Central nervous system lupus

MONDO:0043985

Inflammation that includes the brain, spinal cord and surrounding tissues secondary to systemic lupus erythematosus (SLE); it is associated with neurological and/or psychiatric features.

Also known as: CNS lupus, central nervous system lupus, Meningoencephalitides, lupus, central nervous system lupus vasculitis, central nervous system systemic lupus Erythematosis, lupus Meningoencephalitides, lupus meningoencephalitis, meningoencephalitis, lupus

42 clinical trials for this condition and its sub-types, 3 tagged with Central nervous system lupus itself.

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Where it sits in the disease tree

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↑ Hereditary neurological disease (5791) ↑ Autoimmune disorder of central nervous system (881) ↑ Systemic lupus erythematosus (524)

Including sub-types (42) Tagged with Central nervous system lupus (3)

Trials to join now! 1 Not yet recruiting 1 Completed 1

New hope for lupus brain fog: experimental drug shows promise in trial

Disease control Completed

This study tested an experimental drug called EG-501 for people with lupus who experience cognitive impairment, often called "brain fog." The trial involved 131 participants who received either the drug or a placebo over 14 weeks. The goal was to see if EG-501 could safely improv…

Phase 2 • Sponsor: Evergreen Therapeutics, Inc. • Aim: Disease control

Last updated Jun 27, 2026 08:04 UTC

Central nervous system lupus

Where it sits in the disease tree

New hope for lupus brain fog: experimental drug shows promise in trial