Cataract
MONDO:0005129Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)
Also known as: cataract, cataract (disease), opacity of the lens
306 clinical trials for this condition and its sub-types, 294 tagged with Cataract itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Cataract
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Senile cataract 49 trials · 52 incl. sub-types
2 sub-types
- Nuclear senile cataract 3 trials
- Cortical senile cataract 0 trials
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Nuclear cataract 5 trials · 6 incl. sub-types
1 sub-type
- Nuclear senile cataract 3 trials
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Diabetic cataract 1 trial
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29 sub-types
- Early-onset partial cataract 0 trials · 1 incl. sub-types Sub-types →
- Cataract 10 multiple types 0 trials
- Cataract 11 multiple types 0 trials
- Cataract 13 with adult I phenotype 0 trials
- Cataract 14 multiple types 0 trials
- Cataract 15 multiple types 0 trials
- Cataract 17 multiple types 0 trials
- Cataract 19 multiple types 0 trials
- Cataract 20 multiple types 0 trials
- Cataract 21 multiple types 0 trials
- Cataract 22 multiple types 0 trials
- Cataract 23 0 trials
- Cataract 26 multiple types 0 trials
- Cataract 31 multiple types 0 trials
- Cataract 32 multiple types 0 trials
- Cataract 33 0 trials
- Cataract 38 0 trials
- Cataract 39 multiple types 0 trials
- Cataract 40 0 trials
- Cataract 42 0 trials
- Cataract 43 0 trials
- Cataract 44 0 trials
- Cataract 45 0 trials
- Cataract 46 juvenile-onset 0 trials
- Cataract 5 multiple types 0 trials
- Cataract 6 multiple types 0 trials
- Cataract 8 multiple types 0 trials
- Pulverulent cataract 0 trials
- Total early-onset cataract 0 trials
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Hypermature cataract 1 trial
1 sub-type
- Morgagni cataract 0 trials
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Immature cataract 1 trial
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Mature cataract 1 trial
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Autosomal dominant cataract 0 trials
1 sub-type
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Bhaskar jagannathan syndrome 0 trials
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Cataract 1 multiple types 0 trials
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Cataract 12 multiple types 0 trials
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Cataract 18 0 trials
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Cataract 2, multiple types 0 trials
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Cataract 28 0 trials
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Cataract 29 0 trials
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Cataract 3 multiple types 0 trials
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Cataract 34 multiple types 0 trials
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Cataract 36 0 trials
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Cataract 4 multiple types 0 trials
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Cataract 48 0 trials
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Cataract 49 0 trials
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Cataract 50 with or without glaucoma 0 trials
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Cataract 9 multiple types 0 trials
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Cortical cataract 0 trials
1 sub-type
- Cortical senile cataract 0 trials
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Craniostenosis cataract 0 trials
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Myotonic cataract 0 trials
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Tetanic cataract 0 trials
Most studied deeper sub-types
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New cataract lens shows promise in early trial
Disease control Stopped earlyThis study tested a new type of artificial lens (TECNIS DEN00V) for people having cataract surgery. It compared the new lens to a standard lens in 243 adults with cataracts. The goal was to see if the new lens improves vision at arm's length (66 cm) while keeping good distance vi…
Sponsor: Johnson & Johnson Surgical Vision, Inc. • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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New eye lens aims to sharpen Mid-Range sight after cataracts
Disease control Stopped earlyThis study tested a new type of artificial lens (enVista Aspire) for people having cataract surgery. The goal was to see if it improves intermediate vision, like seeing a computer screen, better than standard lenses. The trial was stopped early and included 27 adults aged 22 and …
Sponsor: Bausch & Lomb Incorporated • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New cataract device tested, but study halted early
Disease control Stopped earlyThis study compared a new device called miCOR, which uses low energy to break up cataracts, to standard cataract surgery. About 402 adults with cataracts were planned to take part. The study was terminated early, so we don't have full results on whether the new device is better o…
Sponsor: Carl Zeiss Meditec, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Can your phone spot eye cancer? app tested for retinoblastoma
Diagnosis Stopped earlyThis study tested a smartphone app called CRADLE that uses a photo to detect leukocoria (a white glow in the pupil), which can be a sign of retinoblastoma, cataracts, or glaucoma. Researchers planned to compare the app's accuracy to a standard eye exam in children with these cond…
Sponsor: St. Jude Children's Research Hospital • Aim: Diagnosis
Last updated Sep 17, 2026 00:00 UTC
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Can a Once-Daily eye drop ease pain and swelling after cataract surgery?
Symptom relief Stopped earlyThis trial tests whether OCS-01, a dexamethasone eye drop, can reduce inflammation and pain after cataract surgery. About 117 adults scheduled for cataract removal will receive either the active drop or a placebo once daily. The study measures how well the drop clears eye inflamm…
Phase 3 • Sponsor: Oculis • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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Tiny study on eye pressure fluctuation in glaucoma patients ends early
Knowledge-focused Stopped earlyThis study aimed to measure how eye volume changes (a sign of pressure fluctuation) before and after cataract surgery in patients with exfoliative glaucoma, a type of glaucoma common in Brittany. Only 6 adults were enrolled before the study was terminated. The goal was to see if …
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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New score could help eye surgeons predict who sees best after surgery
Knowledge-focused Stopped earlyThis study aimed to validate a scoring system that predicts whether patients will have good vision one year after combined cataract and epiretinal membrane surgery. The score uses factors like age, symptom duration, and initial vision. Researchers planned to enroll 164 adults age…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC