Carotid stenosis
MONDO:0001612A narrowing of the carotid artery lumen. It is usually caused by the formation of an atherosclerotic plaque. Symptoms are usually present when there is severe narrowing or obstruction of the arterial lumen and manifest as ischemic cerebrovascular accidents.
Also known as: carotid artery stenosis
110 clinical trials for this condition and its sub-types, 98 tagged with Carotid stenosis itself.
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Statin study halted early: did high doses shield the brain during surgery?
Disease control Stopped earlyThis study looked at whether taking high doses of statins for two weeks before carotid artery surgery could prevent memory and thinking problems after the operation. It included 31 adults with severe carotid artery narrowing. The study was stopped early, so the results are limite…
Phase 3 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Lithium shield: could a mood drug guard the brain during neck surgery?
Disease control Stopped earlyThis study tested whether giving lithium carbonate before carotid artery surgery could reduce brain damage and confusion after the operation. The trial planned to include 107 adults undergoing elective carotid surgery, but it was terminated early. The goal was to see if lithium c…
Phase 3 • Sponsor: Negovsky Reanimatology Research Institute • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New PET tracer aims to reveal hidden immune activity in tumors and arteries
Diagnosis Stopped earlyThis Phase II study tested a radioactive tracer called 68GaNOTA-Anti-MMR-VHH2 to see if it can light up certain immune cells (macrophages) on PET scans. The trial included 29 people with head and neck cancer, lymphoma, atherosclerosis, or sarcoidosis. The goal was to see if the t…
Phase 2 • Sponsor: Universitair Ziekenhuis Brussel • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Gum treatment may slow memory loss in seniors
Prevention Stopped earlyThis study looked at whether intensive treatment for gum disease (periodontitis) could prevent dementia in older adults who already have mild cognitive impairment and narrowed neck arteries. Participants received either standard dental care or deep cleaning and root planing. The …
Sponsor: University of Maryland, Baltimore • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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New monitoring technique for vascular surgery falls short
Knowledge-focused Stopped earlyThis study looked at whether adding a special imaging test (Cytocam-IDF) to standard monitoring during major vascular surgery could help patients leave the hospital sooner. The trial was planned for more participants but was stopped early after only 22 people took part. Because i…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC