Carcinoid heart disease

MONDO:0043529

Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.

Also known as: carcinoid heart disease, carcinoid heart diseases, heart disease, carcinoid, heart diseases, carcinoid

2 clinical trials for this condition and its sub-types, 2 tagged with Carcinoid heart disease itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Heart disorder (6782)

Including sub-types (2) Tagged with Carcinoid heart disease (2)

Not yet recruiting 1 Not yet finished but already full! 1

New valve implant offers hope for rare heart condition

Disease control Ongoing

This study is testing a custom-made artificial heart valve, called TRICENTO, in 15 people with carcinoid heart disease who have severe leakage of the tricuspid valve and cannot have surgery. The valve is delivered through a catheter, avoiding open-heart surgery. The goal is to se…

Sponsor: Queen Mary University of London • Aim: Disease control

Last updated Jun 27, 2026 12:30 UTC

Carcinoid heart disease

Where it sits in the disease tree

New valve implant offers hope for rare heart condition