Calcinosis

This study tests whether a citrate-based dialysis fluid with extra magnesium can slow or prevent blood vessel hardening in adults on long-term hemodialysis. Eighty stable patients will receive either the new fluid or a standard one for 12 months. Researchers will measure blood ma…

This study tests a device that uses sound waves (lithotripsy) to break up calcium buildup in the carotid arteries—the main arteries in the neck—before placing a stent to keep them open. The goal is to see if this approach reduces complications like stroke, heart attack, or death …

This study compares two methods to treat severely calcified coronary arteries: one uses a special balloon that inflates at very high pressure, and the other combines a rotating burr with sound waves to break up calcium. Researchers will enroll 162 adults with hardened arteries to…

Researchers at Massachusetts General Hospital are studying whether molecular imaging and detailed biological profiling can predict how quickly aortic stenosis gets worse. The trial enrolls 100 adults with mild to moderate calcific aortic stenosis. Participants receive a baseline …

This study will use ultrasound to check for medial arterial calcification (hardening of the arteries) in 60 healthy endurance athletes. The goal is to find out how common this condition is in this group and see if it relates to their training habits or heart risk factors. Partici…