Breast intraductal proliferative lesion

MONDO:0004007

A group of non-invasive epithelial proliferations that occur in the ductal system of the breast. The vast majority of cases arise in the terminal ductal lobular units. This category includes atypical ductal hyperplasia, usual ductal hyperplasia, flat epithelial atypia, and ductal carcinoma in situ. There is an increased risk for subsequent development of invasive breast carcinoma.

Also known as: DIN, ductal intraepithelial neoplasia, intraductal proliferative lesion, intraductal proliferative lesion of the breast, mammary intraepithelial neoplasia, ductal type

1594 clinical trials for this condition and its sub-types, 8 tagged with Breast intraductal proliferative lesion itself.

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Where it sits in the disease tree

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Part of

↑ Intraductal breast neoplasm (155)

Sub-types of Breast intraductal proliferative lesion

Ductal breast carcinoma in situ 152 trials
1 sub-type
- Intraductal cribriform breast adenocarcinoma 0 trials
Flat ductal epithelial atypia 3 trials
Usual ductal breast hyperplasia 0 trials

Including sub-types (1594) Tagged with Breast intraductal proliferative lesion (8)

Trials to join now! 1 Not yet recruiting 2 Not yet finished but already full! 2 Completed 2 Terminated 1

Breast cancer prevention study halted: tamoxifen pill vs. gel tested

Prevention Stopped early

This study aimed to see if a tamoxifen skin gel could work as well as the pill to lower breast cancer risk in women with certain high-risk breast conditions. The trial enrolled 65 women and compared short-term changes in breast tissue. However, the study was terminated early, so …

Phase 2 • Sponsor: Mayo Clinic • Aim: Prevention

Last updated Sep 03, 2026 00:00 UTC

Breast intraductal proliferative lesion

Where it sits in the disease tree

Breast cancer prevention study halted: tamoxifen pill vs. gel tested