Breast intraductal proliferative lesion
MONDO:0004007A group of non-invasive epithelial proliferations that occur in the ductal system of the breast. The vast majority of cases arise in the terminal ductal lobular units. This category includes atypical ductal hyperplasia, usual ductal hyperplasia, flat epithelial atypia, and ductal carcinoma in situ. There is an increased risk for subsequent development of invasive breast carcinoma.
Also known as: DIN, ductal intraepithelial neoplasia, intraductal proliferative lesion, intraductal proliferative lesion of the breast, mammary intraepithelial neoplasia, ductal type
1594 clinical trials for this condition and its sub-types, 8 tagged with Breast intraductal proliferative lesion itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Breast intraductal proliferative lesion
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Ductal breast carcinoma in situ 152 trials
1 sub-type
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Flat ductal epithelial atypia 3 trials
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Usual ductal breast hyperplasia 0 trials
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Study comparing Needle-Based breast lesion removal to surgery withdrawn before starting
Knowledge-focused CancelledThis study aimed to compare a less invasive procedure called vacuum-assisted excision (VAPE) to standard surgery for removing non-cancerous but high-risk breast lesions. The goal was to see if VAPE worked as well, was safer, and left better cosmetic results. However, the study wa…
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Breast biopsy aftermath: what patients really feel
Knowledge-focused OngoingThis study looks at how patients feel physically and emotionally after having a breast biopsy for certain non-cancerous but atypical breast conditions. Over 900 participants from several hospitals answered surveys about pain and quality of life, on average nearly four years after…
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC