BRCA1-related cancer predisposition

Hereditary cancer predisposition due to variation(s) in the BRCA1 gene. Germline pathogenic or likely pathogenic variants in the BRCA1 gene confer an autosomal dominant predisposition to hereditary breast and ovarian cancer. Tumor formation at other sites, including pancreatic cancer have been described.

58 clinical trials for this condition and its sub-types, 23 tagged with BRCA1-related cancer predisposition itself.