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Bone giant cell tumor
MONDO:0005674A benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint.
Also known as: GCT of bone, Osteoclastoma, benign, benign bone giant cell tumor, benign bone giant cell tumour, giant cell tumor of bone, giant cell tumor of bone (morphologic abnormality), giant cell tumor of bone NOS (morphologic abnormality), giant cell tumor of the bone
2786 clinical trials for this condition and its sub-types, 7 tagged with Bone giant cell tumor itself.
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Sub-types of Bone giant cell tumor
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Giant cell reparative granuloma 1 trial
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Could your own tumor cells fight cancer? new trial tests immune cell therapy
Disease control OngoingThis phase 2 trial tests a treatment called LN-145, made from a patient's own immune cells taken from their tumor. These cells are grown in a lab and then given back to the patient to attack the cancer. The study includes people with ovarian cancer, triple-negative breast cancer,…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New study tests bone tumor drug in chinese patients
Disease control OngoingThis phase 4 study tests the drug XGEVA (denosumab) in 36 Chinese adults and teens with giant cell tumor of bone, a rare but aggressive bone tumor. Participants receive injections every 4 weeks. The goal is to see if the drug shrinks tumors or helps make surgery easier. The study…
Phase 4 • Sponsor: Amgen • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC