Bone cancer
MONDO:0002129A primary or metastatic malignant neoplasm affecting the bone or articular cartilage.
Also known as: bone neoplasm, bone tumor, bone tumour, osseous tumor, osseous tumour, bone cancer, cancer of bone, cancer of skeletal element
4613 clinical trials for this condition and its sub-types, 79 tagged with Bone cancer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Bone cancer
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Bone marrow cancer 2 trials · 1,631 incl. sub-types
1 sub-type
- Myeloproliferative neoplasm 165 trials · 1,630 incl. sub-types Sub-types →
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Bone carcinoma 0 trials · 131 incl. sub-types
7 sub-types
- Metastatic carcinoma in the bone 107 trials
- Paranasal sinus carcinoma 4 trials · 21 incl. sub-types Sub-types →
- Bone squamous cell carcinoma 0 trials · 11 incl. sub-types Sub-types →
- Pituitary adenocarcinoma 3 trials Sub-types →
- Adamantinoma 0 trials Sub-types →
- Growth hormone-producing pituitary gland carcinoma 0 trials
- Osteosarcoma arising in bone Paget disease 0 trials
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Bone sarcoma 41 trials · 108 incl. sub-types
13 sub-types
- Undifferentiated pleomorphic sarcoma 48 trials Sub-types →
- Dedifferentiated chondrosarcoma 9 trials
- Bone giant cell tumor 7 trials · 8 incl. sub-types Sub-types →
- Bone osteosarcoma 8 trials Sub-types →
- Ewing sarcoma of bone 5 trials
- Undifferentiated high grade pleomorphic sarcoma of bone 4 trials
- Clear cell chondrosarcoma 3 trials
- Malignancy in giant cell tumor of bone 1 trial
- Bone angiosarcoma 0 trials
- Bone fibrosarcoma 0 trials
- Bone leiomyosarcoma 0 trials
- Liposarcoma of bone 0 trials
- Periosteal chondrosarcoma 0 trials
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Primary bone lymphoma 1 trial · 92 incl. sub-types
3 sub-types
- Acute biphenotypic leukemia 88 trials · 91 incl. sub-types Sub-types →
- Paranasal sinus lymphoma 0 trials
- Sternum lymphoma 0 trials
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Skull cancer 0 trials · 38 incl. sub-types
6 sub-types
- Paranasal sinus cancer 4 trials · 24 incl. sub-types Sub-types →
- Jaw cancer 1 trial · 5 incl. sub-types Sub-types →
- Skull base chordoma 5 trials Sub-types →
- Pituitary cancer 2 trials · 4 incl. sub-types Sub-types →
- Orbital cancer 0 trials · 2 incl. sub-types Sub-types →
- Malignant jugulotympanic paraganglioma 0 trials
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Bone chondrosarcoma 1 trial · 10 incl. sub-types
3 sub-types
- Dedifferentiated chondrosarcoma 9 trials
- Clear cell chondrosarcoma 3 trials
- Periosteal chondrosarcoma 0 trials
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Cancer affecting bone of limb skeleton 0 trials · 1 incl. sub-types
4 sub-types
- Cancer of long bone of lower limb 0 trials · 1 incl. sub-types Sub-types →
- Cancer of long bone of upper limb 0 trials
- Cancer of short bone of lower limb 0 trials
- Cancer of short bone of upper limb 0 trials
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Adult extraskeletal osteosarcoma 0 trials
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Chest wall bone cancer 0 trials
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Small cell osteogenic sarcoma 0 trials
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Sternum cancer 0 trials
1 sub-type
- Sternum lymphoma 0 trials
Most studied deeper sub-types
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New hope for young bone cancer patients: drug combo targets tough tumors
Disease control CompletedThis study tests the drug regorafenib in 30 patients aged 9 to 21 with bone cancers (osteosarcoma or Ewing sarcoma) that have not responded to standard therapy. The goal is to see if the drug can help control the disease and improve survival, while also checking its safety. The a…
Phase 1/2 • Sponsor: Institute of Mother and Child, Warsaw, Poland • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Experimental t cell therapy targets sarcoma in small early trial
Disease control CompletedThis early-phase trial tested a personalized cell therapy for people with advanced bone or soft tissue sarcoma that had stopped responding to standard treatment. The therapy uses the patient's own immune cells, modified to better recognize and attack cancer cells carrying a speci…
Phase 1 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New knee prosthesis helps bone cancer patients walk again
Disease control CompletedThis study looked at how well a special knee replacement (MUTARS) works after removing bone cancer. Nine patients were checked to see if they could lock their new knee and walk actively. The goal was to understand if the prosthesis helps with daily movement and walking.
Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Bone paste shows promise in repairing defects after tumor surgery
Disease control CompletedThis study tested a new paste that is placed into bone defects after removing benign tumors or cysts. 29 patients received the paste during surgery and were followed for 12 months. The goal was to see if the paste helps bone heal and is safe to use.
Sponsor: Biovico Sp. z o.o. • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New artery-delivered combo shows promise against bone cancer
Disease control CompletedThis early-phase trial tested a new approach for osteosarcoma (bone cancer) in 10 patients aged 12-40. The treatment combined standard chemotherapy with a targeted drug (Endostar) and cisplatin delivered directly into the artery supplying the tumor. The goal was to see if this me…
Phase 1/2 • Sponsor: Shanghai 6th People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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App helps young cancer survivors shed pounds
Disease control CompletedThis study tested a smartphone app to help young adult cancer survivors (ages 18-39) lose weight. The app tracked diet and activity as part of a behavioral weight loss program. The goal was to see if this approach was practical and well-liked by participants. The study involved 6…
Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Robot arm aims to make bone procedures safer and more precise
Disease control CompletedThis study tested a robotic system called EPIONE that helps doctors guide needles into bones during CT scans. The robot is used for procedures like biopsies, tumor treatments, and bone repairs. Researchers wanted to see if the robot could make these procedures safer and more accu…
Sponsor: Quantum Surgical • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New imaging tool could help spot cancerous bone tumors earlier
Diagnosis CompletedThis study tested a new structured reporting system called BTI-RADS to help doctors better assess bone tumors from X-rays, CT, and MRI scans. Researchers analyzed images from 1,100 patients to see if the tool could more accurately tell which tumors are likely cancerous. The goal …
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Which pain block works best for Kids' thigh surgery?
Symptom relief CompletedThis trial compares two ultrasound-guided pain-relief techniques for children aged 1 to 12 undergoing surgery on the front or side of the thigh. One group receives a fascia iliaca nerve block, while the other gets caudal analgesia, both given after general anesthesia. The goal is…
Sponsor: National Cancer Institute, Egypt • Aim: Symptom relief
Last updated Sep 17, 2026 00:00 UTC
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New study: shoulder surgery helps older cancer patients move better and hurt less
Symptom relief CompletedThis study looked at 53 patients with cancer that spread to the upper arm bone, causing pain and limited movement. Researchers compared older and younger patients who had shoulder replacement surgery to see if age affected recovery. The goal was to find out if this surgery is saf…
Sponsor: Sichuan Provincial People's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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App and brain zaps offer new hope for teen cancer survivors in pain
Symptom relief CompletedThis study looked at whether a mobile cognitive behavioral therapy (CBT) program, combined with a gentle brain stimulation technique called tDCS, could help teens who survived bone cancer manage chronic pain. Researchers first adapted the program for Black and Hispanic teens, the…
Sponsor: St. Jude Children's Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Leg cancer surgery recovery tracked in new study
Knowledge-focused CompletedThis study followed 100 people who had surgery to remove bone or soft tissue tumors in their leg or pelvis. Researchers measured how independent they became in daily activities and how well their joints moved during the first six months after surgery. The goal was simply to descr…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Real-World data reveals gaps in bone cancer care
Knowledge-focused CompletedThis study looked back at the medical records of 545 patients with bone tumors that had spread (metastatic). The goal was to see how these patients were treated in real life and what their outcomes were. The study focused on three types of bone tumors: osteosarcoma, Ewing sarcoma…
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New biobank aims to unlock genetic secrets of rare bone cancer
Knowledge-focused CompletedThis study created a registry and biobank for people with osteosarcoma, a rare bone cancer, and their family members. Researchers collected genetic samples from 362 participants to compare genes of those with and without the disease. The goal is to better understand what causes o…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC