Blood platelet disease
MONDO:0002245Disorders caused by abnormalities in platelet count or function.
Also known as: platelet abnormality, platelet disorder, thrombocytopathy
370 clinical trials for this condition and its sub-types, 18 tagged with Blood platelet disease itself.
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Sub-types of Blood platelet disease
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Thrombocytopenia 75 trials · 267 incl. sub-types
6 sub-types
- Thrombocytopenic purpura 8 trials · 116 incl. sub-types Sub-types →
- Autoimmune thrombocytopenia 8 trials · 113 incl. sub-types Sub-types →
- Thrombocytopenia due to immune destruction 81 trials
- Inherited thrombocytopenia 2 trials · 29 incl. sub-types Sub-types →
- Acquired thrombocytopenia 11 trials · 24 incl. sub-types Sub-types →
- Neonatal thrombocytopenia 5 trials Sub-types →
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Thrombocytosis disease 7 trials · 71 incl. sub-types
3 sub-types
- Essential thrombocythemia 67 trials
- Familial thrombocytosis 2 trials Sub-types →
- Reactive thrombocytosis 0 trials
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Inherited bleeding disorder, platelet-type 6 trials · 26 incl. sub-types
28 sub-types
- Glanzmann thrombasthenia 8 trials Sub-types →
- Platelet-type bleeding disorder 10 8 trials
- Congenital thrombotic thrombocytopenic purpura 5 trials
- Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss 1 trial
- Bernard-Soulier syndrome 0 trials Sub-types →
- Ehlers-Danlos syndrome, fibronectinemic type 0 trials
- Quebec platelet disorder 0 trials
- Scott syndrome 0 trials
- Bleeding diathesis due to thromboxane synthesis deficiency 0 trials
- Bleeding disorder, platelet-type, 21 0 trials
- Bleeding disorder, platelet-type, 22 0 trials
- Bleeding disorder, platelet-type, 24 0 trials
- Bleeding disorder, platelet-type, 25 0 trials
- Cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder 0 trials
- Gray platelet syndrome 0 trials
- Platelet-type bleeding disorder 11 0 trials
- Platelet-type bleeding disorder 12 0 trials
- Platelet-type bleeding disorder 14 0 trials
- Platelet-type bleeding disorder 15 0 trials
- Platelet-type bleeding disorder 16 0 trials
- Platelet-type bleeding disorder 17 0 trials
- Platelet-type bleeding disorder 18 0 trials
- Platelet-type bleeding disorder 19 0 trials
- Platelet-type bleeding disorder 20 0 trials
- Platelet-type bleeding disorder 8 0 trials
- Platelet-type bleeding disorder 9 0 trials
- Platelet-type von Willebrand disease 0 trials
- Primary release disorder of platelets 0 trials
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Qualitative platelet defect 6 trials
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TPM4-related platelet disorder 0 trials
Most studied deeper sub-types
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New injection aims to stabilize platelets in chronic ITP patients
Disease control Recruiting nowThis Phase 3 trial tests whether mezagitamab, given as a shot under the skin, can safely keep platelet counts stable in adults with chronic ITP. ITP is a condition where the immune system destroys platelets, leading to easy bruising and bleeding. The study will compare mezagitama…
Phase 3 • Sponsor: Takeda • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Could a low-dose drug boost blood health in rare platelet disorder?
Disease control Recruiting nowThis study tests whether low-dose sirolimus can safely improve blood cell function in adults with RUNX1 familial platelet disorder, a genetic condition that raises bleeding and leukemia risks. Six participants receive the drug and are monitored for side effects and changes in blo…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New shot shows promise for Long-Term control of bleeding disorder
Disease control Recruiting nowThis study tests the long-term safety of a drug called mezagitamab for adults with chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing easy bruising and bleeding. About 150 participants who completed earlier mezagitamab studies w…
Phase 3 • Sponsor: Takeda • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Blood vessel on a chip could transform bleeding risk tests
Diagnosis Recruiting nowThis study is testing a new device that mimics a blood vessel to evaluate how well a person's blood clots under realistic flow conditions. Researchers will compare results from healthy donors, patients with von Willebrand disease, and those on antiplatelet drugs. The goal is to s…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Diagnosis
Last updated Jun 27, 2026 12:04 UTC
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Can a simple platelet test predict who bleeds after heart surgery?
Knowledge-focused Recruiting nowResearchers are studying whether a preoperative platelet function test can predict heavy bleeding after cardiovascular surgery that uses a heart-lung bypass machine. The study enrolls about 180 adults with normal clotting tests who are not taking antiplatelet drugs and are schedu…
Sponsor: Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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Massive study to track Real-World safety of new blood disorder drugs
Knowledge-focused Recruiting nowThis study is collecting long-term safety and effectiveness data on treatments for various blood disorders, including hemophilia, sickle cell disease, and clotting disorders. It aims to enroll 3000 people of any age with these conditions. Researchers will monitor side effects, co…
Sponsor: American Thrombosis and Hemostasis Network • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Tiny blood cells could hold key to brain tumor treatment
Knowledge-focused Recruiting nowThis study looks at whether platelets—small blood cells that help with clotting—are found inside brain and spinal cord tumors. Researchers want to see if the presence of platelets in these tumors is linked to how long patients survive. The study will involve 50 adults who are hav…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC